Literature DB >> 12410011

Cohort mortality study of German cockpit crew, 1960-1997.

Hajo Zeeb1, Maria Blettner, Gaël P Hammer, Ingo Langner.   

Abstract

BACKGROUND: Cockpit crew in civil aviation are exposed to several potential health hazards, among them cosmic ionizing radiation. To assess the influence of occupational and other factors on mortality we conducted a cohort study among cockpit crew.
METHODS: All pilots and other cockpit personnel of two German airlines were traced through registries and other sources for the period 1960-1997. Standardized mortality ratios, with German population rates as the reference, were calculated. We estimated the individual radiation dose based on individual job histories and assessed dose-response trends in stratified and regression analyses.
RESULTS: We compiled a cohort of 6061 male cockpit personnel, yielding 105,037 person-years of observation. The maximum estimated individual radiation dose was 80.5 mSv. Among 255 deaths overall (standardized mortality ratio [SMR] = 0.48; 95% confidence interval [CI] = 0.42-0.54) there were 76 cancer deaths (SMR = 0.56; CI = 0.43 - 0.74). Most cancer and cardiovascular SMRs were reduced. A slight increase was seen for brain cancer (SMR = 1.68; CI = 0.66-3.62). Employment duration was associated with the all-cancer mortality in Poisson regression analyses. No other dose-response relation was found.
CONCLUSIONS: German cockpit crew have a low overall and cancer mortality. The role of occupational causes, and particularly cosmic radiation, appears limited.

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Year:  2002        PMID: 12410011     DOI: 10.1097/01.EDE.0000029605.69271.8E

Source DB:  PubMed          Journal:  Epidemiology        ISSN: 1044-3983            Impact factor:   4.822


  12 in total

1.  Cosmic radiation and cancer mortality among airline pilots: results from a European cohort study (ESCAPE).

Authors:  I Langner; M Blettner; M Gundestrup; H Storm; R Aspholm; A Auvinen; E Pukkala; G P Hammer; H Zeeb; J Hrafnkelsson; V Rafnsson; H Tulinius; G De Angelis; A Verdecchia; T Haldorsen; U Tveten; H Eliasch; N Hammar; A Linnersjö
Journal:  Radiat Environ Biophys       Date:  2003-11-28       Impact factor: 1.925

2.  Cancer mortality among German aircrew: second follow-up.

Authors:  Hajo Zeeb; Gaël P Hammer; Ingo Langner; Thomas Schafft; Sabrina Bennack; Maria Blettner
Journal:  Radiat Environ Biophys       Date:  2009-10-16       Impact factor: 1.925

3.  Cause-specific mortality in professional flight crew and air traffic control officers: findings from two UK population-based cohorts of over 20,000 subjects.

Authors:  Bianca L De Stavola; Costanza Pizzi; Felicity Clemens; Sally Ann Evans; Anthony D Evans; Isabel dos Santos Silva
Journal:  Int Arch Occup Environ Health       Date:  2011-06-15       Impact factor: 3.015

4.  Estimated radiation exposure of German commercial airline cabin crew in the years 1960-2003 modeled using dose registry data for 2004-2015.

Authors:  Daniel Wollschläger; Gaël Paul Hammer; Thomas Schafft; Steffen Dreger; Maria Blettner; Hajo Zeeb
Journal:  J Expo Sci Environ Epidemiol       Date:  2017-09-20       Impact factor: 5.563

5.  Occupational cosmic radiation exposure in Portuguese airline pilots: study of a possible correlation with oxidative biological markers.

Authors:  Rodrigo Silva; Filipe Folgosa; Paulo Soares; Alice S Pereira; Raquel Garcia; Juan Jesus Gestal-Otero; Pedro Tavares; Marco D R Gomes da Silva
Journal:  Radiat Environ Biophys       Date:  2013-02-15       Impact factor: 1.925

Review 6.  Shift work and cancer: the evidence and the challenge.

Authors:  Thomas C Erren; Puran Falaturi; Peter Morfeld; Peter Knauth; Russel J Reiter; Claus Piekarski
Journal:  Dtsch Arztebl Int       Date:  2010-09-24       Impact factor: 5.594

7.  Cosmic radiation and mortality from cancer among male German airline pilots: extended cohort follow-up.

Authors:  Gaël Paul Hammer; Maria Blettner; Ingo Langner; Hajo Zeeb
Journal:  Eur J Epidemiol       Date:  2012-06-08       Impact factor: 8.082

Review 8.  Chronodisruption and cancer.

Authors:  Thomas C Erren; H Gerd Pape; Russel J Reiter; Claus Piekarski
Journal:  Naturwissenschaften       Date:  2008-01-15

9.  Mortality among a cohort of U.S. commercial airline cockpit crew.

Authors:  Lee C Yong; Lynne E Pinkerton; James H Yiin; Jeri L Anderson; James A Deddens
Journal:  Am J Ind Med       Date:  2014-04-03       Impact factor: 2.214

10.  Adjustment of lifetime risks of space radiation-induced cancer by the healthy worker effect and cancer misclassification.

Authors:  Leif E Peterson; Tatiana Kovyrshina
Journal:  Heliyon       Date:  2015-12-22
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