Literature DB >> 12407348

Examination of the role of abdominal computed tomography in the evaluation of victims of trauma with increased aspartate aminotransferase in the era of focused abdominal sonography for trauma.

Nicole A Stassen1, James K Lukan, Eddy H Carrillo, David A Spain, Lisa A Norfleet, Frank B Miller, Hiram C Polk.   

Abstract

BACKGROUND: Current evaluation of patients with negative findings on a focused abdominal sonography for trauma scan and an isolated increase of admission hepatic enzymes includes abdominal computed tomography (CT). Many of these patients do not have clinically important hepatic injuries. The purpose of this study was to establish the admission aspartate aminotransferase (AST) level below which patients do not need an abdominal CT for injury evaluation and treatment.
METHODS: Patients who were hemodynamically stable, had a focused abdominal sonography for trauma scan with negative findings, and an AST level greater than 200 IU/L were identified over a 1-year period. Medical records were reviewed for demographics, injuries sustained, mechanism, evaluation, interventions, and complications.
RESULTS: A total of 67 patients, mostly with blunt trauma, were identified; 42 (63%) had an AST level < 360 IU/L, and 25 (37%) had an AST level > 360 IU/L. Patients with an AST level > 360 IU/L had a 88% chance of having any hepatic injury and a 44% chance of having an injury of grade III or greater (P =.0001). Patients with an AST level of < 360 IU/L only had a 14% chance of having a liver injury and no chance of having an injury of grade III or greater (P =.036).
CONCLUSIONS: Clinically important hepatic injuries are not missed if an abdominal CT is only performed for patients with a focused abdominal sonography for trauma scan with negative findings and an AST level of > 360 IU/L. Eliminating unnecessary CT allows for more cost-effective use of resources.

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Year:  2002        PMID: 12407348     DOI: 10.1067/msy.2002.127556

Source DB:  PubMed          Journal:  Surgery        ISSN: 0039-6060            Impact factor:   3.982


  6 in total

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Authors:  Bulent Koca; Kagan Karabulut; Gokhan Selcuk Ozbalci; Ayfer Kamali Polat; Ismail Alper Tarim; Bahadir Bulent Gungor; Kenan Erzurumlu
Journal:  Wien Klin Wochenschr       Date:  2015-02-27       Impact factor: 1.704

2.  A Reliable Screening Test to Predict Liver Injury in Pediatric Blunt Torso Trauma.

Authors:  Feng-Yuan Chu; Hung-Jung Lin; How-Ran Guo; Tsan-Hsing Liu; Ning-Ping Foo; Kuo-Tai Chen
Journal:  Eur J Trauma Emerg Surg       Date:  2009-09-05       Impact factor: 3.693

3.  Risk factors for liver abscess formation in patients with blunt hepatic injury after non-operative management.

Authors:  C-P Hsu; S-Y Wang; Y-P Hsu; H-W Chen; B-C Lin; S-C Kang; K-C Yuan; E-H Liu; I-M Kuo; C-H Liao; C-H Ouyang; S-J Yang
Journal:  Eur J Trauma Emerg Surg       Date:  2013-10-24       Impact factor: 3.693

4.  Role of elevated liver transaminase levels in the diagnosis of liver injury after blunt abdominal trauma.

Authors:  Zhiqiang Tian; Hong Liu; Xiaofang Su; Zheng Fang; Zhitao Dong; Changchun Yu; Kunlun Luo
Journal:  Exp Ther Med       Date:  2012-05-15       Impact factor: 2.447

5.  Blunt abdominal trauma patients are at very low risk for intra-abdominal injury after emergency department observation.

Authors:  John L Kendall; Andrew M Kestler; Kurt T Whitaker; Mette-Margrethe Adkisson; Jason S Haukoos
Journal:  West J Emerg Med       Date:  2011-11

6.  Defining the optimal cut-off values for liver enzymes in diagnosing blunt liver injury.

Authors:  Tomohide Koyama; Hirohisa Hamada; Masamichi Nishida; Paal A Naess; Christine Gaarder; Tetsuya Sakamoto
Journal:  BMC Res Notes       Date:  2016-01-25
  6 in total

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