| Literature DB >> 12402171 |
Han Chang1, Meilin Wang, Rong-Tai Tsai, Hui-Sheng Lin, Jin-Shue Huan, Wen-Chuang Wang, Deching Chang.
Abstract
The prevalence of the human JC virus (JCV) in the general population at various ages was investigated. Polymerase chain reaction was employed to detect viral DNA in the urine. The results showed that the incidence of JC viruria was low in the young population, but it was high in the elderly. Hemagglutination inhibition assay was performed for JCV seroprevalence study. The results showed that the seropositive rate of JCV was lower in children than that in adults. The ratio of viruria to seropositive for JCV increased with age and reached 79.7% for those older than 70 years. The results indicated that aging immunity may correlate with JCV reactivation.Entities:
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Year: 2002 PMID: 12402171 DOI: 10.1080/13550280260422758
Source DB: PubMed Journal: J Neurovirol ISSN: 1355-0284 Impact factor: 2.643