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Literature DB >> 6086957

Human polyomavirus JC virus genome.

Abstract

The complete DNA sequence of the human JC virus, which was found to consist of 5,130 nucleotide pairs, is presented. The amino acid sequence of six proteins could be deduced: the early, nonstructural proteins, large T and small t antigens; the late capsid proteins, VP1, VP2, and VP3; and the agnogene product encoded within the late leader sequence, called the agnoprotein in simian virus 40. The extent of homology between JC virus DNA and the genomes of simian virus 40 (69%) and BK virus (75%) confirmed the close evolutionary relationship of these three polyomaviruses. The sequences showing the greatest divergence in these viral DNAs occurred within the tandem repeats located to the late side of the replication origins.

Entities: Gene Species

Mesh：

Substances：

Year: 1984 PMID： 6086957 PMCID： PMC254460

Source DB: PubMed Journal: J Virol ISSN： 0022-538X Impact factor: 5.103

73 in total

1. DNA sequences necessary for transcription of the rabbit beta-globin gene in vivo.

Authors: G C Grosveld; E de Boer; C K Shewmaker; R A Flavell
Journal: Nature Date: 1982-01-14 Impact factor: 49.962

2. A region of the polyoma virus genome between the replication origin and late protein coding sequences is required in cis for both early gene expression and viral DNA replication.

Authors: C Tyndall; G La Mantia; C M Thacker; J Favaloro; R Kamen
Journal: Nucleic Acids Res Date: 1981-12-11 Impact factor: 16.971

3. Identification of a promoter component involved in positioning the 5' termini of simian virus 40 early mRNAs.

Authors: P K Ghosh; P Lebowitz; R J Frisque; Y Gluzman
Journal: Proc Natl Acad Sci U S A Date: 1981-01 Impact factor: 11.205

4. Regulatory sequences and virus-cell interactions of JC virus.

Authors: R J Frisque
Journal: Prog Clin Biol Res Date: 1983

5. Topography of simian virus 40 A protein-DNA complexes: arrangement of pentanucleotide interaction sites at the origin of replication.

Authors: A L DeLucia; B A Lewton; R Tjian; P Tegtmeyer
Journal: J Virol Date: 1983-04 Impact factor: 5.103

6. Definition of the simian virus 40 early promoter region and demonstration of a host range bias in the enhancement effect of the simian virus 40 72-base-pair repeat.

Authors: B J Byrne; M S Davis; J Yamaguchi; D J Bergsma; K N Subramanian
Journal: Proc Natl Acad Sci U S A Date: 1983-02 Impact factor: 11.205

7. Nucleotide sequence of the region encompassing the JC virus origin of DNA replication.

Authors: R J Frisque
Journal: J Virol Date: 1983-04 Impact factor: 5.103

8. Use of whole-cell fixation to visualize replicating and maturing simian virus 40: identification of new viral gene product.

Authors: V Jackson; R Chalkley
Journal: Proc Natl Acad Sci U S A Date: 1981-10 Impact factor: 11.205

9. A small segment of polyoma virus DNA enhances the expression of a cloned beta-globin gene over a distance of 1400 base pairs.

Authors: J de Villiers; W Schaffner
Journal: Nucleic Acids Res Date: 1981-12-11 Impact factor: 16.971

10. Simian virus 40 tumor antigen: isolation of the origin-specific DNA-binding domain.

Authors: B Morrison; M Kress; G Khoury; G Jay
Journal: J Virol Date: 1983-07 Impact factor: 5.103

268 in total

1. Reciprocal interaction between two cellular proteins, Puralpha and YB-1, modulates transcriptional activity of JCVCY in glial cells.

Authors: M Safak; G L Gallia; K Khalili
Journal: Mol Cell Biol Date: 1999-04 Impact factor: 4.272

Review 2. A classification scheme for human polyomavirus JCV variants based on the nucleotide sequence of the noncoding regulatory region.

Authors: P N Jensen; E O Major
Journal: J Neurovirol Date: 2001-08 Impact factor: 2.643

3. Increased frequency of JC virus type 2 and of dual infection with JC virus type 1 and 2 in Italian progressive multifocal leukoencephalopathy patients.

Authors: P Ferrante; M Mediati; R Caldarelli-Stefano; L Losciale; R Mancuso; A E Cagni; R Maserati
Journal: J Neurovirol Date: 2001-02 Impact factor: 2.643

Review 4. Structure and function of JC virus T' proteins.

Authors: R J Frisque
Journal: J Neurovirol Date: 2001-08 Impact factor: 2.643

Review 5. T' proteins influence JC virus biology.

Authors: Richard J Frisque; Brigitte Bollag; Shiva K Tyagarajan; Lisa H Kilpatrick
Journal: J Neurovirol Date: 2003 Impact factor: 2.643

6. Analysis of DNA-binding activity of the JC virus minor capsid protein VP2.

Authors: Yih-Leh Huang; Meilin Wang; Wei-Chih Ou; Chiung-Yau Fung; Li-Sheng Chen; Deching Chang
Journal: J Neurovirol Date: 2003 Impact factor: 2.643

7. JC virus quasispecies analysis reveals a complex viral population underlying progressive multifocal leukoencephalopathy and supports viral dissemination via the hematogenous route.

Authors: Tom Van Loy; Kim Thys; Caroline Ryschkewitsch; Ole Lagatie; Maria C Monaco; Eugene O Major; Luc Tritsmans; Lieven J Stuyver
Journal: J Virol Date: 2014-11-12 Impact factor: 5.103

8. JC virus regulatory region tandem repeats in plasma and central nervous system isolates correlate with poor clinical outcome in patients with progressive multifocal leukoencephalopathy.

Authors: L A Pfister; N L Letvin; I J Koralnik
Journal: J Virol Date: 2001-06 Impact factor: 5.103

9. JC virus promoter/enhancers contain TATA box-associated Spi-B-binding sites that support early viral gene expression in primary astrocytes.

Authors: Leslie J Marshall; Lisa D Moore; Matthew M Mirsky; Eugene O Major
Journal: J Gen Virol Date: 2011-11-09 Impact factor: 3.891

10. Direct isolation and characterization of JC virus from urine samples of renal and bone marrow transplant patients.

Authors: C Myers; R J Frisque; R R Arthur
Journal: J Virol Date: 1989-10 Impact factor: 5.103