Literature DB >> 12401489

siRNA. A guide for RNA silencing.

Gopalakrishna Ramaswamy1, Frank J Slack.   

Abstract

RNAi is routinely used to eliminate gene activity for experimental purposes. However, the precise molecular mechanism of RNAi is unknown. Recent papers partially illuminate this mechanism in human cells, advancing the potential application of RNAi toward the treatment of human disease.

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Year:  2002        PMID： 12401489     DOI： 10.1016/s1074-5521(02)00249-1

Source DB:  PubMed          Journal:  Chem Biol        ISSN： 1074-5521


  5 in total

1.  In vitro gene targeting in human hepatoblastoma.

Authors:  Steven W Warmann; Sorin Armeanu; Heike Frank; Heike Buck; Florian Graepler; Marie-Luise Lemken; Heike Heitmann; Guido Seitz; Ulrich M Lauer; Michael Bitzer; Jörg Fuchs
Journal:  Pediatr Surg Int       Date:  2006-01       Impact factor: 1.827

2.  Complete, gene-specific siRNA libraries: production and expression in mammalian cells.

Authors:  Attila A Seyhan; Alexander V Vlassov; Heini Ilves; Levente Egry; Roger L Kaspar; Sergei A Kazakov; Brian H Johnston
Journal:  RNA       Date:  2005-05       Impact factor: 4.942

3.  Search for a prion-specific nucleic acid.

Authors:  Jiri G Safar; Klaus Kellings; Ana Serban; Darlene Groth; James E Cleaver; Stanley B Prusiner; Detlev Riesner
Journal:  J Virol       Date:  2005-08       Impact factor: 5.103

4.  Suppression of Mamu-AG by RNA interference.

Authors:  Jessica G Drenzek; Jolanta Vidiguriene; Geminis Vidiguris; Richard L Grendell; Svetlana V Dambaeva; Maureen Durning; Thaddeus G Golos
Journal:  Am J Reprod Immunol       Date:  2009-04-22       Impact factor: 3.886

5.  Dicer functions in aquatic species.

Authors:  Yasuko Kitagishi; Naoko Okumura; Hitomi Yoshida; Chika Tateishi; Yuri Nishimura; Satoru Matsuda
Journal:  J Amino Acids       Date:  2011-06-09
  5 in total

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