Literature DB >> 12400871

Studies on adjuvanticity of sodium houttuyfonate and its mechanism.

Dayong Wang1, Qinghai Yu, Peggy Eikstadt, Darcy Hammond, Yun Feng, Na Chen.   

Abstract

The adjuvanticity of sodium houttuyfonate (SH) and its mechanism were studied in this research. Significant enhancement of antibody production was observed when co-injected with antigen. The levels of anti-BSA antibodies were measured by enzyme-linked immunosorbent assay (ELISA). The possible mechanism of this phenomenon was also investigated in this research, which included the effects of SH on the phagocytosis of macrophages, the production of lysozyme, acid phosphotase and IL-1beta generated by macrophages, the proliferation of the lymphocytes in spleen and the production of IL-2 generated by lymphocytes. IL-1beta is a co-stimulator in activating Th cells, which manifests its activity together with LFA-1, ICAM-1 and ICAM-2. These observations suggested that SH could be used as a new adjuvant.

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Year:  2002        PMID： 12400871     DOI： 10.1016/s1567-5769(02)00060-7

Source DB:  PubMed          Journal:  Int Immunopharmacol        ISSN： 1567-5769            Impact factor:   4.932


  8 in total

1.  Sodium houttuyfonate in vitro inhibits biofilm dispersion and expression of bdlA in Pseudomonas aeruginosa.

Authors:  Tianming Wang; Weifeng Huang; Qiangjun Duan; Jian Wang; Huijuan Cheng; Jing Shao; Fang Li; Daqiang Wu
Journal:  Mol Biol Rep       Date:  2018-12-03       Impact factor: 2.316

2.  Sodium houttuyfonate inhibits biofilm formation and alginate biosynthesis-associated gene expression in a clinical strain of Pseudomonas aeruginosa in vitro.

Authors:  DA-Qiang Wu; Huijuan Cheng; Qiangjun Duan; Weifeng Huang
Journal:  Exp Ther Med       Date:  2015-06-10       Impact factor: 2.447

3.  Chemiluminescence determination of sodium new houttuyfonate in pharmaceutical preparations based on tween 80-rhodamine B system.

Authors:  Xiao-Feng Yang; Hanchun Yao; Ji-Bao Zhai; Hua Li
Journal:  J Fluoresc       Date:  2006-12-12       Impact factor: 2.217

4.  The immune enhancement of sodium lauryl sulfoacetate in chickens.

Authors:  Darong Cheng; Shanyuan Zhu; Huaichang Sun
Journal:  Vet Med Int       Date:  2010-05-04

Review 5.  A current update on the phytopharmacological aspects of Houttuynia cordata Thunb.

Authors:  Manish Kumar; Satyendra K Prasad; S Hemalatha
Journal:  Pharmacogn Rev       Date:  2014-01

6.  Sodium houttuyfonate affects production of N-acyl homoserine lactone and quorum sensing-regulated genes expression in Pseudomonas aeruginosa.

Authors:  Daqiang Wu; Weifeng Huang; Qiangjun Duan; Fang Li; Huijuan Cheng
Journal:  Front Microbiol       Date:  2014-11-26       Impact factor: 5.640

7.  Transcriptional and functional analysis shows sodium houttuyfonate-mediated inhibition of autolysis in Staphylococcus aureus.

Authors:  Guoxing Liu; Hua Xiang; Xudong Tang; Kaiyu Zhang; Xiuping Wu; Xuelin Wang; Na Guo; Haihua Feng; Guangming Wang; Lihui Liu; Qiyun Shi; Fengge Shen; Mingxun Xing; Peng Yuan; Mingyuan Liu; Lu Yu
Journal:  Molecules       Date:  2011-10-21       Impact factor: 4.411

8.  Immune response of AA broilers to IBV H120 vaccine and sodium new houttuyfonate.

Authors:  Yefei Zhou; Meixian Zhou; Dunlin Zhang; Honglin Zhang; Liyang Zhang
Journal:  Res Vet Sci       Date:  2010-05-06       Impact factor: 2.534
  8 in total

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