Literature DB >> 1239490

Interferon induction by viruses and polynucleotides: a differential effect of comptothecin.

K T Atherton, D C Burke.   

Abstract

The plant alkaloid comptothecin inhibits interferon production induced by Newcastle disease virus (NDV) or ultraviolet-irradiated NDV in chick and human cells, and by Sindbis virus in chick cells. It has no effect on interferon production induced by poly (rI).poly(rC) in chick and human cells. No effect of comptothecin could be detected on the multiplication of NDV, and it is concluded that the inhibition reflects a difference between interferon induction by viruses and by polynucleotides.

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Year:  1975        PMID： 1239490     DOI： 10.1099/0022-1317-29-3-297

Source DB:  PubMed          Journal:  J Gen Virol        ISSN： 0022-1317            Impact factor:   3.891


  8 in total

1.  Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation.

Authors:  Alex Rialdi; Laura Campisi; Nan Zhao; Arvin Cesar Lagda; Colette Pietzsch; Jessica Sook Yuin Ho; Luis Martinez-Gil; Romain Fenouil; Xiaoting Chen; Megan Edwards; Giorgi Metreveli; Stefan Jordan; Zuleyma Peralta; Cesar Munoz-Fontela; Nicole Bouvier; Miriam Merad; Jian Jin; Matthew Weirauch; Sven Heinz; Chris Benner; Harm van Bakel; Christopher Basler; Adolfo García-Sastre; Alexander Bukreyev; Ivan Marazzi
Journal:  Science       Date:  2016-04-28       Impact factor: 47.728

2.  Interferon assay as a diagnostic test.

Authors:  R P Parry; J V Parry
Journal:  Lancet       Date:  1981-02-28       Impact factor: 79.321

3.  Interferon production: variation in yields from human cell lines.

Authors:  A Meager; H E Graves; J Shuttleworth; N Zucker
Journal:  Infect Immun       Date:  1979-08       Impact factor: 3.441

4.  Toxicity of interferon.

Authors:  G M Scott; D S Secher; D Flowers; J Bate; K Cantell; D A Tyrrell
Journal:  Br Med J (Clin Res Ed)       Date:  1981-04-25

5.  High-level expression of an interferon alpha 2 gene cloned in phage M13mp7 and subsequent purification with a monoclonal antibody.

Authors:  P Slocombe; A Easton; P Boseley; D C Burke
Journal:  Proc Natl Acad Sci U S A       Date:  1982-09       Impact factor: 11.205

6.  Expression in Saccharomyces cerevisiae of human interferon-alpha directed by the TRP1 5' region.

Authors:  M J Dobson; M F Tuite; J Mellor; N A Roberts; R M King; D C Burke; A J Kingsman; S M Kingsman
Journal:  Nucleic Acids Res       Date:  1983-04-25       Impact factor: 16.971

7.  Interferon induction with Newcastle disease virus in FS-4 cells: effect of 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole (DRB).

Authors:  M Kohase; J Vilcek
Journal:  Arch Virol       Date:  1979       Impact factor: 2.574

8.  Regulated high efficiency expression of human interferon-alpha in Saccharomyces cerevisiae.

Authors:  M F Tuite; M J Dobson; N A Roberts; R M King; D C Burke; S M Kingsman; A J Kingsman
Journal:  EMBO J       Date:  1982       Impact factor: 11.598
  8 in total

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