Literature DB >> 12392909

Developmental changes in lysosome morphology and function Leishmania parasites.

Ross F Waller1, Malcolm J McConville.   

Abstract

The endocytic pathway of Leishmania parasites has recently come under intense research focus through the development of several markers for various compartments of this pathway. Through these studies a novel multivesicular tubule lysosome has been discovered in promastigote-stage parasites. This organelle has a highly dynamic role during parasite growth and differentiation. This review discusses recent insights into the Leishmania lysosome with respect to its organisation within the endocytic pathway, stage-specific functions, and biogenesis.

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Year:  2002        PMID： 12392909     DOI： 10.1016/s0020-7519(02)00140-6

Source DB:  PubMed          Journal:  Int J Parasitol        ISSN： 0020-7519            Impact factor:   3.981


  16 in total

Review 1.  Autophagy in protists.

Authors:  Michael Duszenko; Michael L Ginger; Ana Brennand; Melisa Gualdrón-López; María Isabel Colombo; Graham H Coombs; Isabelle Coppens; Bamini Jayabalasingham; Gordon Langsley; Solange Lisboa de Castro; Rubem Menna-Barreto; Jeremy C Mottram; Miguel Navarro; Daniel J Rigden; Patricia S Romano; Veronika Stoka; Boris Turk; Paul A M Michels
Journal:  Autophagy       Date:  2011-02-01       Impact factor: 16.016

2.  Antileishmanial activity of parthenolide, a sesquiterpene lactone isolated from Tanacetum parthenium.

Authors:  Tatiana Shioji Tiuman; Tânia Ueda-Nakamura; Diógenes Aparício Garcia Cortez; Benedito Prado Dias Filho; José Andrés Morgado-Díaz; Wanderley de Souza; Celso Vataru Nakamura
Journal:  Antimicrob Agents Chemother       Date:  2005-01       Impact factor: 5.191

Review 3.  Autophagy in unicellular eukaryotes.

Authors:  Jan A K W Kiel
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2010-03-12       Impact factor: 6.237

4.  Leishmania salvage and remodelling of host sphingolipids in amastigote survival and acidocalcisome biogenesis.

Authors:  Kai Zhang; Fong-Fu Hsu; David A Scott; Roberto Docampo; John Turk; Stephen M Beverley
Journal:  Mol Microbiol       Date:  2005-03       Impact factor: 3.501

5.  Adaptor protein complex 1 mediates the transport of lysosomal proteins from a Golgi-like organelle to peripheral vacuoles in the primitive eukaryote Giardia lamblia.

Authors:  María C Touz; Liudmila Kulakova; Theodore E Nash
Journal:  Mol Biol Cell       Date:  2004-04-23       Impact factor: 4.138

6.  All Trypanosoma cruzi developmental forms present lysosome-related organelles.

Authors:  Celso Sant'Anna; Fabiola Parussini; Daniela Lourenço; Wanderley de Souza; Juan Jose Cazzulo; Narcisa Leal Cunha-e-Silva
Journal:  Histochem Cell Biol       Date:  2008-08-12       Impact factor: 4.304

7.  Regulated expression of the Leishmania major surface virulence factor lipophosphoglycan using conditionally destabilized fusion proteins.

Authors:  Luciana Madeira da Silva; Katherine L Owens; Silvane M F Murta; Stephen M Beverley
Journal:  Proc Natl Acad Sci U S A       Date:  2009-04-21       Impact factor: 11.205

8.  Ultrastructural and cytochemical identification of megasome in Leishmania (Leishmania) chagasi.

Authors:  Sanny O Alberio; Suzana S Dias; Flávio P Faria; Renato A Mortara; Clara L Barbiéri; Edna Freymüller Haapalainen
Journal:  Parasitol Res       Date:  2004-01-09       Impact factor: 2.289

9.  Sphingolipids are essential for differentiation but not growth in Leishmania.

Authors:  Kai Zhang; Melissa Showalter; Javier Revollo; Fong-Fu Hsu; John Turk; Stephen M Beverley
Journal:  EMBO J       Date:  2003-11-17       Impact factor: 11.598

10.  A potential role for ICP, a Leishmanial inhibitor of cysteine peptidases, in the interaction between host and parasite.

Authors:  Sébastien Besteiro; Graham H Coombs; Jeremy C Mottram
Journal:  Mol Microbiol       Date:  2004-12       Impact factor: 3.501
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