Literature DB >> 12377233

Triterpenoids from the leaves of Psidium guajava.

Sabira Begum1, Syed Imran Hassan, Bina S Siddiqui, Farhana Shaheen, M Nabeel Ghayur, Anwar H Gilani.   

Abstract

Two triterpenoids, 20beta-acetoxy-2alpha,3beta-dihydroxyurs-12-en-28-oic acid (guavanoic acid, 3), and 2alpha,3beta-dihydroxy-24-p-z-coumaroyloxyurs-12-en-28-oic acid (guavacoumaric acid, 7), along with six known compounds 2alpha-hydroxyursolic acid (1), jacoumaric acid (2), isoneriucoumaric acid (4), asiatic acid (5), ilelatifol D (6) and beta-sitosterol-3-O-beta-D-glucopyranoside (8), have been isolated from the leaves of Psidium guajava. Their structures were determined through spectroscopic methods. Compound 5 showed dose-dependent (10-500 microg/ml) spasmolytic activity in spontaneously contracting isolated rabbit jejunum preparations.

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Year:  2002        PMID： 12377233     DOI： 10.1016/s0031-9422(02)00190-5

Source DB:  PubMed          Journal:  Phytochemistry        ISSN： 0031-9422            Impact factor:   4.072


  14 in total

Review 1.  Pharmacological Properties, Molecular Mechanisms, and Pharmaceutical Development of Asiatic Acid: A Pentacyclic Triterpenoid of Therapeutic Promise.

Authors:  Mohamed Fizur Nagoor Meeran; Sameer N Goyal; Kapil Suchal; Charu Sharma; Chandragouda R Patil; Shreesh K Ojha
Journal:  Front Pharmacol       Date:  2018-09-04       Impact factor: 5.810

2.  Intestinal ameliorative effects of traditional Ogi-tutu, Vernonia amygdalina and Psidium guajava in mice infected with Vibrio cholera.

Authors:  Olufunke B Shittu; Olusola L Ajayi; Samuel O Bankole; Temitope Os Popoola
Journal:  Afr Health Sci       Date:  2016-06       Impact factor: 0.927

3.  In-vitro antibacterial activity of selected medicinal plants from Longisa region of Bomet district, Kenya.

Authors:  K R Cheruiyot; D Olila; J Kateregga
Journal:  Afr Health Sci       Date:  2009-08-01       Impact factor: 0.927

4.  Guava extract (Psidium guajava) alters the labelling of blood constituents with technetium-99m.

Authors:  P R C Abreu; M C Almeida; R M Bernardo; L C Bernardo; L C Brito; E A C Garcia; A S Fonseca; M Bernardo-Filho
Journal:  J Zhejiang Univ Sci B       Date:  2006-06       Impact factor: 3.066

5.  Evolution of a Strategy for the Enantioselective Total Synthesis of (+)-Psiguadial B.

Authors:  Lauren M Chapman; Jordan C Beck; Caitlin R Lacker; Linglin Wu; Sarah E Reisman
Journal:  J Org Chem       Date:  2018-05-18       Impact factor: 4.354

6.  Comparative antimicrobial efficacy of herbal alternatives (Emblica officinalis, Psidium guajava), MTAD, and 2.5% sodium hypochlorite against Enterococcus faecalis: An in vitro study.

Authors:  Sandeep Dubey
Journal:  J Oral Biol Craniofac Res       Date:  2016-01-20

7.  A study of the anti-inflammatory effect of the leaves of Psidium guajava Linn. on experimental animal models.

Authors:  Sarmistha Dutta; Swarnamoni Das
Journal:  Pharmacognosy Res       Date:  2010-09

8.  Virtual Screening of Indonesian Herbal Database as HIV-1 Protease Inhibitor.

Authors:  Arry Yanuar; Heru Suhartanto; Abdul Munim; Bram Hik Anugraha; Rezi Riadhi Syahdi
Journal:  Bioinformation       Date:  2014-02-19

9.  Bioactivity determination of methanol and water extracts for roots and leaves of Kenyan Psidium guajava L landraces against pathogenic bacteria.

Authors:  Mercy Liharaka Kidaha; Amos Emitati Alakonya; Aggrey Benard Nyende
Journal:  Springerplus       Date:  2013-12-13

10.  Effect of Aqueous Extract of Psidium Guajava Leaves on Liver Enzymes, Histological Integrity and Hematological Indices in Rats.

Authors:  Friday E Uboh; Iniobong E Okon; Moses B Ekong
Journal:  Gastroenterology Res       Date:  2010-01-20
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