BACKGROUND: Axillary lymph node dissection (ALND) is often associated with permanent arm side effects. Side effects after sentinel lymph node dissection (SLND) should be less common, because the surgery is less extensive. METHODS: The study compared side effects and interference with daily life between 169 women who underwent an SLND and 78 who underwent an ALND for breast cancer. Patients rated symptom severity and interference with daily life caused by pain, numbness, limitation of arm range of motion (ROM), and arm swelling at 1, 6, and 12 months after surgery by using the Measure of Arm Symptom Survey. Repeated-measures and regression analyses for each time period were used to determine associations between symptoms and dissection type. RESULTS: At 1 month, SLND patients reported less pain, numbness, limitation in ROM, and seromas than ALND patients. At 6 months, SLND patients had less pain, numbness, and arm swelling, and at 12 months, SLND patients had less numbness, arm swelling, and limitation in ROM than ALND patients. At 1 month, pain, numbness, and limitation in ROM interfered significantly more with daily life for ALND patients. At 6 and 12 months, only numbness interfered more with daily life for ALND patients. CONCLUSIONS: SLND was associated with fewer side effects than ALND at all time points.
BACKGROUND: Axillary lymph node dissection (ALND) is often associated with permanent arm side effects. Side effects after sentinel lymph node dissection (SLND) should be less common, because the surgery is less extensive. METHODS: The study compared side effects and interference with daily life between 169 women who underwent an SLND and 78 who underwent an ALND for breast cancer. Patients rated symptom severity and interference with daily life caused by pain, numbness, limitation of arm range of motion (ROM), and arm swelling at 1, 6, and 12 months after surgery by using the Measure of Arm Symptom Survey. Repeated-measures and regression analyses for each time period were used to determine associations between symptoms and dissection type. RESULTS: At 1 month, SLND patients reported less pain, numbness, limitation in ROM, and seromas than ALNDpatients. At 6 months, SLND patients had less pain, numbness, and arm swelling, and at 12 months, SLND patients had less numbness, arm swelling, and limitation in ROM than ALND patients. At 1 month, pain, numbness, and limitation in ROM interfered significantly more with daily life for ALND patients. At 6 and 12 months, only numbness interfered more with daily life for ALND patients. CONCLUSIONS: SLND was associated with fewer side effects than ALND at all time points.
Authors: Kristin L Schreiber; Nantthansorn Zinboonyahgoon; K Mikayla Flowers; Valerie Hruschak; Kara G Fields; Megan E Patton; Emily Schwartz; Desiree Azizoddin; Mieke Soens; Tari King; Ann Partridge; Andrea Pusic; Mehra Golshan; Rob R Edwards Journal: Ann Surg Oncol Date: 2021-01-15 Impact factor: 5.344
Authors: M T Bajén; A Benítez; J Mora; Y Ricart; N Ferran; S Guirao; D Carrera; M Gil; M J Pla; A Gumá; J A Palacin; J Martin-Comin Journal: Eur J Nucl Med Mol Imaging Date: 2005-11-24 Impact factor: 9.236
Authors: Li Wang; Gordon H Guyatt; Sean A Kennedy; Beatriz Romerosa; Henry Y Kwon; Alka Kaushal; Yaping Chang; Samantha Craigie; Carlos P B de Almeida; Rachel J Couban; Shawn R Parascandalo; Zain Izhar; Susan Reid; James S Khan; Michael McGillion; Jason W Busse Journal: CMAJ Date: 2016-07-11 Impact factor: 8.262
Authors: Marco Esposito; Benjamin Busam; Christoph Hennersperger; Julia Rackerseder; Nassir Navab; Benjamin Frisch Journal: Int J Comput Assist Radiol Surg Date: 2016-08-09 Impact factor: 2.924
Authors: Jan J Kootstra; Josette E H M Hoekstra-Weebers; Johan S Rietman; Jakob de Vries; Peter C Baas; Jan H B Geertzen; Harald J Hoekstra Journal: Ann Surg Oncol Date: 2010-03-11 Impact factor: 5.344