Literature DB >> 1237148

The action of ionizing radiation on DNA in the presence of quinacrine. II. DNA strand breakage.

A Hissung, H Dertinger.   

Abstract

Strand breakage of DNA irradiated in solution and in the dry state in the presence of quinacrine was investigated by sedimentation analysis. Determination of single strand breaks in solution combined with binding studies permits to conclude that bound quinacrine protects DNA more effectively than the free compound. In the dry state quinacrine is without detectable effect on both single and double strand break formation, neither under aerobic nor anaerobic conditions.

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Year:  1975        PMID： 1237148     DOI： 10.1007/bf02339805

Source DB:  PubMed          Journal:  Radiat Environ Biophys        ISSN： 0301-634X            Impact factor:   1.925


  7 in total

1.  INTERRUPTIONS IN THE POLYNUCLEOTIDE STRANDS IN BACTERIOPHAGE DNA.

Authors:  P F DAVISON; D FREIFELDER; B W HOLLOWAY
Journal:  J Mol Biol       Date:  1964-01       Impact factor: 5.469

2.  The action of ionizing radiation on DNA in the presence of quinacrine. I. UV absorption and fluorescence measurements.

Authors:  A Hissung; H Dertinger; G Heinrich
Journal:  Radiat Environ Biophys       Date:  1975-06-13       Impact factor: 1.925

3.  The action of ionizing radiation on DNA in the presence of quinacrine. III. E.S.R. study: spin transfer in gamma-irradiated lyophilized DNA-quinacrine complexes.

Authors:  A Hissung; K F Weibezahn
Journal:  Radiat Environ Biophys       Date:  1976-07-30       Impact factor: 1.925

4.  Oxygen effect in gamma-irradiated DNA.

Authors:  C Lücke-Huhle; A Braun; U Hagen
Journal:  Z Naturforsch B       Date:  1970-11       Impact factor: 1.047

5.  Exciton-like splitting in acridine dye-nucleic acid complexes.

Authors:  M Nastasi; R W Yip; V L Seligy; A G Szabo; R E Williams
Journal:  Nature       Date:  1974-05-17       Impact factor: 49.962

6.  The interaction of aminocridines with nucleic acids.

Authors:  A Blake; A R Peacocke
Journal:  Biopolymers       Date:  1968       Impact factor: 2.505

7.  [Studies on the radiation effect on deoxyribonucleic acid. 3. Fractionation and cross linkings following direct irradiation].

Authors:  U Hagen; H Wellstein
Journal:  Strahlentherapie       Date:  1965-12
  7 in total
  2 in total

1.  The action of ionizing radiation on DNA in the presence of quinacrine. I. UV absorption and fluorescence measurements.

Authors:  A Hissung; H Dertinger; G Heinrich
Journal:  Radiat Environ Biophys       Date:  1975-06-13       Impact factor: 1.925

2.  The action of ionizing radiation on DNA in the presence of quinacrine. III. E.S.R. study: spin transfer in gamma-irradiated lyophilized DNA-quinacrine complexes.

Authors:  A Hissung; K F Weibezahn
Journal:  Radiat Environ Biophys       Date:  1976-07-30       Impact factor: 1.925
  2 in total

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