Literature DB >> 12370042

Malaria: new chemotherapeutic peroxide drugs.

Kristina Borstnik1, Ik-Hyeon Paik, Gary H Posner.   

Abstract

Chemical insights into artemisinin's biological mechanism of action have allowed rational design of some new trioxane and endoperoxide antimalarial drug candidates that are efficacious and safe. This review summarizes recent achievements in this area of peroxide drug development for malaria chemotherapy.

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Year:  2002        PMID： 12370042     DOI： 10.2174/1389557023405620

Source DB:  PubMed          Journal:  Mini Rev Med Chem        ISSN： 1389-5575            Impact factor:   3.862


  4 in total

1.  Artemisinin as a Chinese medicine, selectively induces apoptosis in pancreatic tumor cell line.

Authors:  Shokoofe Noori; Zuhair M Hassan; Vida Farsam
Journal:  Chin J Integr Med       Date:  2013-06-15       Impact factor: 1.978

2.  Artemisinin and a series of novel endoperoxide antimalarials exert early effects on digestive vacuole morphology.

Authors:  Maria del Pilar Crespo; Thomas D Avery; Eric Hanssen; Emma Fox; Tony V Robinson; Peter Valente; Dennis K Taylor; Leann Tilley
Journal:  Antimicrob Agents Chemother       Date:  2007-10-15       Impact factor: 5.191

Review 3.  Prodrugs for the treatment of neglected diseases.

Authors:  Man Chin Chung; Elizabeth Igne Ferreira; Jean Leandro Santos; Jeanine Giarolla; Daniela Gonçales Rando; Adélia Emília Almeida; Priscila Longhin Bosquesi; Renato Farina Menegon; Lorena Blau
Journal:  Molecules       Date:  2007-03-19       Impact factor: 4.411

Review 4.  Structural basis for endoperoxide-forming oxygenases.

Authors:  Takahiro Mori; Ikuro Abe
Journal:  Beilstein J Org Chem       Date:  2022-06-21       Impact factor: 2.544
  4 in total

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