Literature DB >> 12361227

Novel synthesis and antifungal activity of pyrrole and pyrrolo[2,3-d]pyrimidine derivatives containing sulfonamido moieties.

M S A El-Gaby1, A M Gaber, A A Atalla, K A Abd Al-Wahab.   

Abstract

Several sulfonamides containing pyrroles (2a-c, 6a-d, 8a-d), pyrrolo[2,3-d] pyrimidines (3a-c), acetanilides (11a-c) and tetrahydrobenzothiophenes (13a-c) were synthesized starting from N4-chloroacetylsulfanilamides (1a-d). The structures of synthesized compounds were elucidated by elemental analyses and spectral data. Compounds 2b, 3b, 6b, 8b and 8d exhibited a remarkable antifungal activity compared with the standard fungicide mycostatine.

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Year:  2002        PMID： 12361227     DOI： 10.1016/s0014-827x(01)01178-8

Source DB:  PubMed          Journal:  Farmaco        ISSN： 0014-827X


  8 in total

1.  One-pot multicomponent synthesis of diversely substituted 2-aminopyrroles. A short general synthesis of rigidins A, B, C, and D.

Authors:  Liliya V Frolova; Nikolai M Evdokimov; Kathryn Hayden; Indranil Malik; Snezna Rogelj; Alexander Kornienko; Igor V Magedov
Journal:  Org Lett       Date:  2011-01-26       Impact factor: 6.005

2.  Synthesis and antimicrobial evaluation of some novel thiazole, pyridone, pyrazole, chromene, hydrazone derivatives bearing a biologically active sulfonamide moiety.

Authors:  Elham S Darwish; Azza M Abdel Fattah; Fawzy A Attaby; Oqba N Al-Shayea
Journal:  Int J Mol Sci       Date:  2014-01-17       Impact factor: 5.923

3.  Bis-pyrimidine acetamides: design, synthesis and biological evaluation.

Authors:  Sanjiv Kumar; Siong Meng Lim; Kalavathy Ramasamy; Mani Vasudevan; Syed Adnan Ali Shah; Balasubramanian Narasimhan
Journal:  Chem Cent J       Date:  2017-08-08       Impact factor: 4.215

4.  Synthesis of some novel pyrazolo[3,4-d] pyrimidin-4(5H)-one derivatives as potential antimicrobial agent.

Authors:  Dipen K Sureja; Sandip P Dholakia; Kantilal R Vadalia
Journal:  J Pharm Bioallied Sci       Date:  2016 Oct-Dec

5.  Synthesis and evaluation of novel pyrroles and pyrrolopyrimidines as anti-hyperglycemic agents.

Authors:  M S Mohamed; S A Ali; D H A Abdelaziz; Samar S Fathallah
Journal:  Biomed Res Int       Date:  2014-06-26       Impact factor: 3.411

6.  Facile synthesis and antimicrobial evaluation of some new heterocyclic compounds incorporating a biologically active sulfamoyl moiety.

Authors:  Elham S Darwish
Journal:  ScientificWorldJournal       Date:  2014-08-17

Review 7.  Therapeutic potential of heterocyclic pyrimidine scaffolds.

Authors:  Sanjiv Kumar; Balasubramanian Narasimhan
Journal:  Chem Cent J       Date:  2018-04-04       Impact factor: 4.215

8.  Design, synthesis, antimicrobial and cytotoxicity study on human colorectal carcinoma cell line of new 4,4'-(1,4-phenylene)bis(pyrimidin-2-amine) derivatives.

Authors:  Sanjiv Kumar; Siong Meng Lim; Kalavathy Ramasamy; Vasudevan Mani; Syed Adnan Ali Shah; Balasubramanian Narasimhan
Journal:  Chem Cent J       Date:  2018-06-25       Impact factor: 4.215
  8 in total

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