| Literature DB >> 12360193 |
Abstract
Members of the structural maintenance of chromosomes (SMC) family share a characteristic design and configuration of protein domains that provides the molecular basis for the various functions of this family in chromosome dynamics. SMC proteins have a role in chromosome condensation, sister-chromatid cohesion, DNA repair and recombination, and gene dosage compensation, and they function in somatic and meiotic cells. As more is learned about how their unique design affects their function, a picture of a dynamic and varied protein family is emerging.Mesh：
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Year: 2002 PMID： 12360193 DOI： 10.1038/nrm930
Source DB: PubMed Journal: Nat Rev Mol Cell Biol ISSN： 1471-0072 Impact factor: 94.444