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Literature DB >> 12354901

High prevalence of cagA- and babA2-positive Helicobacter pylori clinical isolates in Taiwan.

Chih-Ho Lai¹, Chun-Hsien Kuo, Ya-Chi Chen, Fang-Yu Chao, Sek-Kwong Poon, Chi-Sen Chang, Wen-Ching Wang.

Abstract

Two virulence markers, cagA and babA2, were characterized by PCR in 101 Helicobacter pylori isolates from a population in Taiwan. cagA was detected in 99% of the isolates, while babA2 was present in all of the isolates. Base deletions and substitutions at the forward babA2 primer annealing sites were found. Given their high prevalence, cagA and babA2 cannot be useful markers for predicting the high-risk patients of H. pylori infection in Taiwan.

Entities: Disease Gene Species

Mesh：

Substances：

Year: 2002 PMID： 12354901 PMCID： PMC130881 DOI： 10.1128/JCM.40.10.3860-3862.2002

Source DB: PubMed Journal: J Clin Microbiol ISSN： 0095-1137 Impact factor: 5.948

28 in total

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7. Prevalence of Helicobacter pylori vacA, cagA, cagE, iceA, babA2, and oipA genotypes in patients with upper gastrointestinal diseases.

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