Literature DB >> 1235053

Carcinogenicity of 4-hydroxybutyl-butylnitrosamine in Syrian hamsters.

J Althoff, F W Krüger.   

Abstract

4-Hydroxybutyl-butylnitrosamine (HBBN), a urinary metabolite of dibutylnitrosamine (DBN) was shown to induce respiratory and bile duct tumors as well as carcinomas of the urinary bladder in Syrian golden hamsters. This contrasts with results previously obtained in rats and demonstrates that HBBN is not a specific bladder carcinogen. Bronchogenic tumors, seen in DBN-treated hamsters, were not observed after injection of HBBN.

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Year:  1975        PMID: 1235053     DOI: 10.1016/s0304-3835(75)94625-x

Source DB:  PubMed          Journal:  Cancer Lett        ISSN: 0304-3835            Impact factor:   8.679


  4 in total

1.  Transplacental effect of nitrosamines in Syrian hamsters. IV. Metabolites of dipropyl- and dibutylnitrosamine.

Authors:  J Althoff; C Grandjean; P Pour
Journal:  Z Krebsforsch Klin Onkol Cancer Res Clin Oncol       Date:  1977-11-18

2.  Comparison of the effect of beta-oxidized dipropylnitrosamine metabolites administered at equimolar doses to Syrian hamsters.

Authors:  J Althoff; C Grandjean; P Pour; B Bertram
Journal:  Z Krebsforsch Klin Onkol Cancer Res Clin Oncol       Date:  1977-11-18

3.  Urinary bladder neoplasms in Syrian hamsters after administration of N-nitroso-N-methyl-N-dodecylamine.

Authors:  J Althoff; W Lijinsky
Journal:  Z Krebsforsch Klin Onkol Cancer Res Clin Oncol       Date:  1977-12-15

Review 4.  Preclinical Models for Bladder Cancer Research.

Authors:  Shaoming Zhu; Zheng Zhu; Ai-Hong Ma; Guru P Sonpavde; Fan Cheng; Chong-Xian Pan
Journal:  Hematol Oncol Clin North Am       Date:  2021-04-16       Impact factor: 2.861

  4 in total

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