Literature DB >> 1233268

General theory for rapidly establishing steady state drug concentrations using two consecutive constant rate intravenous infusions.

D P Vaughan, G T Tucker.   

Abstract

Steady state plasma drug concentrations can be achieved rapidly and safely by a drug input mode consisting of two consecutive constant rate intravenous infusions. A general method for calculating the relative rates of the two infusions is presented. The derivation is independent of the concepts of compartmental distribution and elimination of drugs within the body.

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Year:  1975        PMID： 1233268     DOI： 10.1007/bf00614023

Source DB:  PubMed          Journal:  Eur J Clin Pharmacol        ISSN： 0031-6970            Impact factor:   2.953


  13 in total

1.  Pharmacology of local anaesthetic agents. Pharmacokinetics of local anaesthetic agents.

Authors:  G T Tucker; L E Mather
Journal:  Br J Anaesth       Date:  1975-02       Impact factor: 9.166

2.  The pharmacokinetics of inulin and urea: a comparison of the dose eliminated from a compartmental model and that eliminated in urine.

Authors:  G R Bourne; H E Barber
Journal:  J Pharm Pharmacol       Date:  1972-07       Impact factor: 3.765

3.  Pharmacokinetics of absorption, distribution and elimination of fenfluramine and its main metabolite in man.

Authors:  A H Beckett; J A Salmon
Journal:  J Pharm Pharmacol       Date:  1972-02       Impact factor: 3.765

4.  Comparative pharmacokinetics of coumarin anticoagulants. IV. Application of a three-compartmental model to the analysis of the dose-dependent kinetics of bishydroxycoumarin elimination.

Authors:  R Nagashima; G Levy; R A O'Reilly
Journal:  J Pharm Sci       Date:  1968-11       Impact factor: 3.534

5.  Pharmacokinetics of intravenous theophylline.

Authors:  P A Mitenko; R I Ogilvie
Journal:  Clin Pharmacol Ther       Date:  1973 Jul-Aug       Impact factor: 6.875

6.  General treatment of linear mammillary models with elimination from any compartment as used in pharmacokinetics.

Authors:  L Z Benet
Journal:  J Pharm Sci       Date:  1972-04       Impact factor: 3.534

7.  Pharmacokinetics of lidocaine in man.

Authors:  R N Boyes; D B Scott; P J Jebson; M J Godman; D G Julian
Journal:  Clin Pharmacol Ther       Date:  1971 Jan-Feb       Impact factor: 6.875

8.  Some pharmacokinetic aspects of 5-(dimethylriazeno)-imidazole-4-carboxamide in the dog.

Authors:  T L Loo; B B Tanner; G E Housholder; B J Shepard
Journal:  J Pharm Sci       Date:  1968-12       Impact factor: 3.534

9.  Pharmacokinetic aspects of intravenous regional anesthesia.

Authors:  G T Tucker; R A Boas
Journal:  Anesthesiology       Date:  1971-06       Impact factor: 7.892

10.  Pharmacokinetics of pentazocine in the rhesus monkey.

Authors:  K A Pittman; G A Portmann
Journal:  J Pharm Sci       Date:  1974-01       Impact factor: 3.534
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  5 in total

1.  Pharmacokinetics of intravenous N-acetylcysteine in men at rest and during exercise.

Authors:  Malcolm Brown; Andrew Bjorksten; Ivan Medved; Michael McKenna
Journal:  Eur J Clin Pharmacol       Date:  2004-11-20       Impact factor: 2.953

2.  A model-independent proof of Dost's law of corresponding areas.

Authors:  D P Vaughan
Journal:  J Pharmacokinet Biopharm       Date:  1977-06

3.  Pharmacokinetic data. Pharmacokinetic parameters estimated from intravenous data by uniform methods and some of their uses.

Authors:  J G Wagner
Journal:  J Pharmacokinet Biopharm       Date:  1977-04

Review 4.  Pharmacodynamics and pharmacokinetics of thiopental.

Authors:  H Russo; F Bressolle
Journal:  Clin Pharmacokinet       Date:  1998-08       Impact factor: 6.447

5.  Evaluation of infusion regimens for thiopentone as a primary anaesthetic agent.

Authors:  D P Crankshaw; N E Edwards; G L Blackman; M D Boyd; H N Chan; D J Morgan
Journal:  Eur J Clin Pharmacol       Date:  1985       Impact factor: 2.953
  5 in total

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