Literature DB >> 1227509

Role of cytosolic rat liver aldehyde dehydrogenase in the oxidation of acetaldehyde during ethanol metabolism in vivo.

C J Eriksson, M Marselos, T Koivula.   

Abstract

The activity of a high-Km aldehyde dehydrogenase in the liver cytosol was increased by phenobarbital induction. No corresponding increase in the oxidation rate of acetaldehyde in vivo was found, and it is concluded that cytosolic aldehyde dehydrogenase plays only a minor role in the oxidation of acetaldehyde during ethanol metabolism.

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Year:  1975        PMID： 1227509      PMCID： PMC1172529          DOI： 10.1042/bj1520709

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  13 in total

1.  [On the metabolite content and the metabolite concentration in the liver of the rat].

Authors:  H J HOHORST; F H KREUTZ; T BUECHER
Journal:  Biochem Z       Date:  1959

2.  Different forms of rat liver aldehyde dehydrogenase and their subcellular distribution.

Authors:  T Koivula; M Koivusalo
Journal:  Biochim Biophys Acta       Date:  1975-07-27

3.  Intracellular localization of aldehyde dehydrogenase in rat liver.

Authors:  L Marjanen
Journal:  Biochem J       Date:  1972-05       Impact factor: 3.857

4.  Induction of liver acetaldehyde dehydrogenase: possible role in ethanol tolerance after exposure tobarbiturates.

Authors:  G Redmond; G Cohen
Journal:  Science       Date:  1971-01-29       Impact factor: 47.728

5.  Genetic aspects of increase in rat liver aldehyde dehydrogenase induced by phenobarbital.

Authors:  R A Deitrich
Journal:  Science       Date:  1971-07-23       Impact factor: 47.728

6.  Genetic influence upon phenobarbital-induced increase in rat liver supernatant aldehyde dehydrogenase activity.

Authors:  R A Deitrich; A C Collins; V G Erwin
Journal:  J Biol Chem       Date:  1972-11-25       Impact factor: 5.157

7.  Micro method for determination of ketone bodies by head-space gas chromatography.

Authors:  C J Eriksson
Journal:  Anal Biochem       Date:  1972-05       Impact factor: 3.365

8.  The subcellular distribution and properties of aldehyde dehydrogenases in rat liver.

Authors:  S O Tottmar; H Pettersson; K H Kiessling
Journal:  Biochem J       Date:  1973-12       Impact factor: 3.857

9.  Utilization and metabolic effects of acetaldehyde and ethanol in the perfused rat liver.

Authors:  K O Lindros; R Vihma; O A Forsander
Journal:  Biochem J       Date:  1972-02       Impact factor: 3.857

10.  Ethanol and acetaldehyde metabolism in rat strains genetically selected for their ethanol preference.

Authors:  C J Eriksson
Journal:  Biochem Pharmacol       Date:  1973-09-15       Impact factor: 5.858
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  8 in total

Review 1.  Environmental Aldehyde Sources and the Health Implications of Exposure.

Authors:  Pritam Sinharoy; Stacy L McAllister; Megana Vasu; Eric R Gross
Journal:  Adv Exp Med Biol       Date:  2019       Impact factor: 2.622

2.  Rates of induction of mitochondrial aldehyde dehydrogenase in rat liver.

Authors:  A A Horton; M C Barrett
Journal:  Biochem J       Date:  1976-04-15       Impact factor: 3.857

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Authors:  Eric R Gross; Vanessa O Zambelli; Bryce A Small; Julio C B Ferreira; Che-Hong Chen; Daria Mochly-Rosen
Journal:  Annu Rev Pharmacol Toxicol       Date:  2014-09-29       Impact factor: 13.820

4.  Characterization of superoxide production from aldehyde oxidase: an important source of oxidants in biological tissues.

Authors:  Tapan Kumar Kundu; Russ Hille; Murugesan Velayutham; Jay L Zweier
Journal:  Arch Biochem Biophys       Date:  2007-01-23       Impact factor: 4.013

5.  The importance of alcohol dehydrogenase in regulation of ethanol metabolism in rat liver cells.

Authors:  R A Page; K E Kitson; M J Hardman
Journal:  Biochem J       Date:  1991-09-15       Impact factor: 3.857

6.  Aldehyde dehydrogenase-2 regulates nociception in rodent models of acute inflammatory pain.

Authors:  Vanessa O Zambelli; Eric R Gross; Che-Hong Chen; Vanessa P Gutierrez; Yara Cury; Daria Mochly-Rosen
Journal:  Sci Transl Med       Date:  2014-08-27       Impact factor: 17.956

7.  Ethanol and Acetaldehyde After Intraperitoneal Administration to Aldh2-Knockout Mice-Reflection in Blood and Brain Levels.

Authors:  Mostofa Jamal; Kiyoshi Ameno; Naoko Tanaka; Asuka Ito; Ayaka Takakura; Mitsuru Kumihashi; Hiroshi Kinoshita
Journal:  Neurochem Res       Date:  2015-12-08       Impact factor: 3.996

8.  Suppressive Effect of Shiitake Extract on Plasma Ethanol Elevation.

Authors:  Harumi Uto-Kondo; Ayaka Sakurai; Kazuki Ogawa; Yusuke Yamaguchi; Takeshi Saito; Hitomi Kumagai
Journal:  Nutrients       Date:  2020-08-31       Impact factor: 5.717
  8 in total

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