Literature DB >> 12271806

Neurocognitive dimensions characterising patients with first-episode psychosis.

S Friis1, K Sundet, B R Rund, P Vaglum, T H McGlashan.   

Abstract

BACKGROUND: Assessment of neurocognitive dysfunction in schizophrenia is hampered by the multitude of tests used in the literature. AIMS: We aimed to identify the main dimensions of an assessment battery for patients with first-episode psychosis and to estimate the relationship between dimension scores and gender, age, education, diagnosis and symptoms.
METHOD: Eight frequently used neuropsychological tests were used. We tested 219 patients 3 months after start of therapy or at remission, whichever occurred first.
RESULTS: We identified five dimensions: working memory (WM); verbal learning (VL); executive function (EF); impulsivity (im); and motor speed (MS). Significant findings were that the MS score was higher for men, and the WM and VL scores were correlated with years of education.
CONCLUSIONS: Neurocognitive function in first-episode psychosis is described by at least five independent dimensions.

Entities:  

Mesh:

Year:  2002        PMID: 12271806     DOI: 10.1192/bjp.181.43.s85

Source DB:  PubMed          Journal:  Br J Psychiatry Suppl        ISSN: 0960-5371


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