Literature DB >> 12270181

Cytotoxic activity of aminoderivatized cationic chitosan derivatives.

Jung-Kul Lee1, Hyun-Soo Lim, Jung-Hoe Kim.   

Abstract

Chitosan derivatives were prepared by dialkylaminoalkylation and reductive amination followed by quaternization. In this study, the cytotoxic activity of the chitosan derivatives was investigated and a relationship between structure and activity is suggested. The cationic chitosan derivatives elicited dose-dependent inhibitory effects on the proliferation of tumor cell lines.

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Year:  2002        PMID： 12270181     DOI： 10.1016/s0960-894x(02)00530-9

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  7 in total

1.  In vitro effects of chitosan nanoparticles on proliferation of human gastric carcinoma cell line MGC803 cells.

Authors:  Li-Feng Qi; Zi-Rong Xu; Yan Li; Xia Jiang; Xin-Yan Han
Journal:  World J Gastroenterol       Date:  2005-09-07       Impact factor: 5.742

2.  'In Vitro', 'In Vivo' and 'In Silico' Investigation of the Anticancer Effectiveness of Oxygen-Loaded Chitosan-Shelled Nanodroplets as Potential Drug Vector.

Authors:  Amina Khadjavi; Ilaria Stura; Mauro Prato; Valerio Giacomo Minero; Alice Panariti; Ilaria Rivolta; Giulia Rossana Gulino; Federica Bessone; Giuliana Giribaldi; Elena Quaglino; Roberta Cavalli; Federica Cavallo; Caterina Guiot
Journal:  Pharm Res       Date:  2018-02-26       Impact factor: 4.200

3.  Preparation, characterisation and preliminary antitumour activity evaluation of a novel nanoparticulate system based on a cisplatin-hyaluronate complex and N-trimethyl chitosan.

Authors:  Sergio Cafaggi; Eleonora Russo; Rossana Stefani; Brunella Parodi; Gabriele Caviglioli; Greta Sillo; Angela Bisio; Cinzia Aiello; Maurizio Viale
Journal:  Invest New Drugs       Date:  2009-12-29       Impact factor: 3.850

4.  Downregulation of CD147 by chitooligosaccharide inhibits MMP-2 expression and suppresses the metastatic potential of human gastric cancer.

Authors:  Zhiguo Luo; Xiaoxia Dong; Qing Ke; Qiwen Duan; Li Shen
Journal:  Oncol Lett       Date:  2014-05-07       Impact factor: 2.967

Review 5.  Crustacean Waste-Derived Chitosan: Antioxidant Properties and Future Perspective.

Authors:  Manikandan Muthu; Judy Gopal; Sechul Chun; Anna Jacintha Prameela Devadoss; Nazim Hasan; Iyyakkannu Sivanesan
Journal:  Antioxidants (Basel)       Date:  2021-02-03

Review 6.  In vitro models in biocompatibility assessment for biomedical-grade chitosan derivatives in wound management.

Authors:  Lim Chin Keong; Ahmad Sukari Halim
Journal:  Int J Mol Sci       Date:  2009-03-18       Impact factor: 6.208

Review 7.  A review on chitosan and its development as pulmonary particulate anti-infective and anti-cancer drug carriers.

Authors:  Ruhisy Mohd Rasul; M Tamilarasi Muniandy; Zabliza Zakaria; Kifayatullah Shah; Chin Fei Chee; Ali Dabbagh; Noorsaadah Abd Rahman; Tin Wui Wong
Journal:  Carbohydr Polym       Date:  2020-08-18       Impact factor: 9.381
  7 in total

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