Literature DB >> 12240953

Interactions of n-tetraalkylammonium compounds and biguanides with a human renal organic cation transporter (hOCT2).

Mark J Dresser1, Guangqing Xiao, Maya K Leabman, Andrew T Gray, Kathleen M Giacomini.   

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Year:  2002        PMID： 12240953     DOI： 10.1023/a:1019870831174

Source DB:  PubMed          Journal:  Pharm Res        ISSN： 0724-8741            Impact factor:   4.200


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  17 in total

1.  Role of organic cation transporters in the renal secretion of nucleosides.

Authors:  R Chen; J A Nelson
Journal:  Biochem Pharmacol       Date:  2000-07-15       Impact factor: 5.858

2.  Properties and regulation of organic cation transport in freshly isolated human proximal tubules.

Authors:  G Pietig; T Mehrens; J R Hirsch; I Cetinkaya; H Piechota; E Schlatter
Journal:  J Biol Chem       Date:  2001-07-10       Impact factor: 5.157

3.  Serine 318 is essential for the pyrimidine selectivity of the N2 Na+-nucleoside transporter.

Authors:  J Wang; K M Giacomini
Journal:  J Biol Chem       Date:  1999-01-22       Impact factor: 5.157

4.  Reduced hepatic uptake and intestinal excretion of organic cations in mice with a targeted disruption of the organic cation transporter 1 (Oct1 [Slc22a1]) gene.

Authors:  J W Jonker; E Wagenaar; C A Mol; M Buitelaar; H Koepsell; J W Smit; A H Schinkel
Journal:  Mol Cell Biol       Date:  2001-08       Impact factor: 4.272

Review 5.  Renal drug transport: a review.

Authors:  R Bendayan
Journal:  Pharmacotherapy       Date:  1996 Nov-Dec       Impact factor: 4.705

6.  The interaction of n-tetraalkylammonium compounds with a human organic cation transporter, hOCT1.

Authors:  L Zhang; W Gorset; M J Dresser; K M Giacomini
Journal:  J Pharmacol Exp Ther       Date:  1999-03       Impact factor: 4.030

Review 7.  Biguanides and NIDDM.

Authors:  C J Bailey
Journal:  Diabetes Care       Date:  1992-06       Impact factor: 19.112

8.  Reduction of metformin renal tubular secretion by cimetidine in man.

Authors:  A Somogyi; C Stockley; J Keal; P Rolan; F Bochner
Journal:  Br J Clin Pharmacol       Date:  1987-05       Impact factor: 4.335

9.  Functional characteristics and membrane localization of rat multispecific organic cation transporters, OCT1 and OCT2, mediating tubular secretion of cationic drugs.

Authors:  Y Urakami; M Okuda; S Masuda; H Saito; K I Inui
Journal:  J Pharmacol Exp Ther       Date:  1998-11       Impact factor: 4.030

10.  Disposition of metformin (N,N-dimethylbiguanide) in man.

Authors:  C R Sirtori; G Franceschini; M Galli-Kienle; G Cighetti; G Galli; A Bondioli; F Conti
Journal:  Clin Pharmacol Ther       Date:  1978-12       Impact factor: 6.875
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  22 in total

1.  Cimetidine does not appear to influence the distribution of metformin into human milk.

Authors:  Sharon J Gardiner; Carl M J Kirkpatrick; Mei Zhang; Evan J Begg
Journal:  Br J Clin Pharmacol       Date:  2008-06-09       Impact factor: 4.335

2.  Molecular analysis and structure-activity relationship modeling of the substrate/inhibitor interaction site of plasma membrane monoamine transporter.

Authors:  Horace T B Ho; Yongmei Pan; Zhiyi Cui; Haichuan Duan; Peter W Swaan; Joanne Wang
Journal:  J Pharmacol Exp Ther       Date:  2011-08-04       Impact factor: 4.030

Review 3.  A review of the clinical pharmacokinetics and pharmacodynamics of varenicline for smoking cessation.

Authors:  Hélène M Faessel; R Scott Obach; Hans Rollema; Patanjali Ravva; Kathryn E Williams; Aaron H Burstein
Journal:  Clin Pharmacokinet       Date:  2010-12       Impact factor: 6.447

Review 4.  Renal Drug Transporters and Drug Interactions.

Authors:  Anton Ivanyuk; Françoise Livio; Jérôme Biollaz; Thierry Buclin
Journal:  Clin Pharmacokinet       Date:  2017-08       Impact factor: 6.447

5.  Case Study 7: Transporters Case Studies-In Vitro Solutions for Translatable Outcomes.

Authors:  Sid Bhoopathy; Chris Bode; Vatsala Naageshwaran; Erica Weiskircher-Hildebrandt; Venkata Mukkavilli; Ismael J Hidalgo
Journal:  Methods Mol Biol       Date:  2021

6.  Characterization of the inhibitory effects of N-butylpyridinium chloride and structurally related ionic liquids on organic cation transporters 1/2 and human toxic extrusion transporters 1/2-k in vitro and in vivo.

Authors:  Yaofeng Cheng; Lucy J Martinez-Guerrero; Stephen H Wright; Robert K Kuester; Michelle J Hooth; I Glenn Sipes
Journal:  Drug Metab Dispos       Date:  2011-06-06       Impact factor: 3.922

7.  Metformin transport by renal basolateral organic cation transporter hOCT2.

Authors:  Naoko Kimura; Masahiro Okuda; Ken-ichi Inui
Journal:  Pharm Res       Date:  2005-02       Impact factor: 4.200

8.  Multiple mechanisms of ligand interaction with the human organic cation transporter, OCT2.

Authors:  Jaclyn N Harper; Stephen H Wright
Journal:  Am J Physiol Renal Physiol       Date:  2012-10-03

9.  Effect of genetic variation in the organic cation transporter 1 (OCT1) on metformin action.

Authors:  Yan Shu; Steven A Sheardown; Chaline Brown; Ryan P Owen; Shuzhong Zhang; Richard A Castro; Alexandra G Ianculescu; Lin Yue; Joan C Lo; Esteban G Burchard; Claire M Brett; Kathleen M Giacomini
Journal:  J Clin Invest       Date:  2007-05       Impact factor: 14.808

10.  Pharmacogenetics of Anti-Diabetes Drugs.

Authors:  Johanna K Distefano; Richard M Watanabe
Journal:  Pharmaceuticals (Basel)       Date:  2010-08-01
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