Literature DB >> 12238809

Histometric study of socket healing after tooth extraction in rats treated with diclofenac.

Luciana Ibara Yugoshi1, Miguel Angel Sala, Luiz Guilherme Brentegani, Teresa Lúcia Lamano Carvalho.   

Abstract

The purpose of the present study was to investigate if diclofenac administration interferes with the time course of alveolar wound healing in rats. Forty-two Wistar rats were used, 21 rats received 10 mg/kg/day of diclofenac one day before and 4 days after extraction of the right maxillary incisors and 21 rats received saline. The animals were sacrificed 7, 14 and 21 days after tooth extraction. Progressive new bone formation and a decrease in the volume fraction of blood clot and connective tissue from 1 to 3 weeks after tooth extraction was quantified using the histometric point-counting method. Diclofenac treatment caused a significant delay in new bone formation in association with an impairment of blood clot remission/organization.

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Year:  2002        PMID： 12238809     DOI： 10.1590/s0103-64402002000200003

Source DB:  PubMed          Journal:  Braz Dent J        ISSN： 0103-6440


  11 in total

1.  Alveolar bone healing process in spontaneously hypertensive rats (SHR). A radiographic densitometry study.

Authors:  Natalia Manrique; Cassiano Costa Silva Pereira; Lourdes Maria Gonzáles Garcia; Samuel Micaroni; Antonio Augusto Ferreira de Carvalho; Sílvia Helena Venturoli Perri; Roberta Okamoto; Doris Hissako Sumida; Cristina Antoniali
Journal:  J Appl Oral Sci       Date:  2012 Mar-Apr       Impact factor: 2.698

2.  Hypertension modifies OPG, RANK, and RANKL expression during the dental socket bone healing process in spontaneously hypertensive rats.

Authors:  Natalia Manrique; Cassiano Costa Silva Pereira; Eloá Rodrigues Luvizuto; Maria Del Pilar Rodriguez Sánchez; Tetuo Okamoto; Roberta Okamoto; Doris H Sumida; Cristina Antoniali
Journal:  Clin Oral Investig       Date:  2015-01-07       Impact factor: 3.573

3.  Isotretinoin effect on alveolar repair after exodontia--a study in rats.

Authors:  Roberta Dalmolin Bergoli; Otacilio Luiz Chagas Junior; Carlos Eduardo Chrzanowski Pereira de Souza; Beatriz Farias Vogt; Henrique Telles Ramos de Oliveira; Adriana Etges; Daniela Nascimento Silva
Journal:  Oral Maxillofac Surg       Date:  2010-07-25

4.  Treatment with paracetamol, ketorolac or etoricoxib did not hinder alveolar bone healing: a histometric study in rats.

Authors:  Ricardo Nogueira Fracon; Juliana Mazzonetto Teófilo; Izabela Cristina Moris; Teresa Lamano
Journal:  J Appl Oral Sci       Date:  2010-12       Impact factor: 2.698

5.  Effects of topical nasal steroids and diclofenac on the nasal mucosa during hyperbaric oxygen therapy: a double-blind experimental study.

Authors:  Erkan Vuralkan; Hatice Bengu Cobanoglu; Abdullah Arslan; Selcuk Arslan; Sevdegul Mungan; Selcuk Tatar; Akın Savas Toklu
Journal:  Eur Arch Otorhinolaryngol       Date:  2013-12-22       Impact factor: 2.503

6.  The Influence of Different Nonsteroidal Anti-Inflammatory Drugs on Alveolar Bone in Rats: An Experimental Study.

Authors:  Mujgan Gungor Hatipoglu; Sermet Inal; Sahin Kabay; Muhammet Kasim Cayci; Ayşenur Deger; Halil Isa Kuru; Sayit Altikat; Gizem Akkas
Journal:  Acta Stomatol Croat       Date:  2015-12

7.  The effects of a nonsteroidal anti-inflammatory drug on the degree of titanium implant osseointegration.

Authors:  Vesile Elif Toy; Serkan Dundar; Alihan Bozoglan
Journal:  J Oral Biol Craniofac Res       Date:  2020-07-03

8.  Intramembranous bone healing process subsequent to tooth extraction in mice: micro-computed tomography, histomorphometric and molecular characterization.

Authors:  Andreia Espindola Vieira; Carlos Eduardo Repeke; Samuel de Barros Ferreira Junior; Priscila Maria Colavite; Claudia Cristina Biguetti; Rodrigo Cardoso Oliveira; Gerson Francisco Assis; Rumio Taga; Ana Paula Favaro Trombone; Gustavo Pompermaier Garlet
Journal:  PLoS One       Date:  2015-05-29       Impact factor: 3.240

9.  Comparative evaluation of the efficacy of the cyclooxygenase pathway inhibitor and nitric oxide synthase inhibitor in the reduction of alveolar bone loss in ligature induced periodontitis in rats: An experimental study.

Authors:  Rekha Jagadish; Dhoom Singh Mehta
Journal:  J Indian Soc Periodontol       Date:  2014-01

10.  Carbonate Apatite Containing Statin Enhances Bone Formation in Healing Incisal Extraction Sockets in Rats.

Authors:  Yunia Dwi Rakhmatia; Yasunori Ayukawa; Akihiro Furuhashi; Kiyoshi Koyano
Journal:  Materials (Basel)       Date:  2018-07-12       Impact factor: 3.623
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