Literature DB >> 12237556

New biologically active marine sesquiterpenoid and steroid from the okinawan sponge of the genus Axinyssa.

Makoto Iwashima1, Ikuo Terada, Kazuo Iguchi, Takao Yamori.   

Abstract

A new bisabolane-type sesquiterpenoid, (E)-3-isocyanobisabolane-7,10-diene (1), and a new epidioxyergostane-type steroid, 9(11)-dehydroaxinysterol (2), were isolated from the Okinawan sponge of the genus Axinyssa. Their structures were elucidated based on the results of spectroscopic analysis and chemical conversion. Epidioxysterol 2 was found to show significant growth inhibitory effects against human cancer cell lines.

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Year:  2002        PMID: 12237556     DOI: 10.1248/cpb.50.1286

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN: 0009-2363            Impact factor:   1.645


  5 in total

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Journal:  Mar Drugs       Date:  2020-12-21       Impact factor: 5.118

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Review 4.  Chemistry and Bioactivity of Marine-Derived Bisabolane Sesquiterpenoids: A Review.

Authors:  Cheng-Shou Li; Li-Ting Liu; Lei Yang; Jing Li; Xin Dong
Journal:  Front Chem       Date:  2022-04-07       Impact factor: 5.545

Review 5.  Terpenoids in Marine Heterobranch Molluscs.

Authors:  Conxita Avila
Journal:  Mar Drugs       Date:  2020-03-14       Impact factor: 5.118

  5 in total

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