Literature DB >> 12230011

Anti-inflammatory and hepatoprotective activity of peh-hue-juwa-chi-cao in male rats.

Chun-Ching Lin1, Lean-Teik Ng, Jenq-Jer Yang, Yu-Fang Hsu.   

Abstract

Peh-hue-juwa-chi-cao (PHJCC) is a common commercial name for the herbal extract of either Hedyotis diffusa (HD), H. corymbosa (HC), or Mollugo pentaphylla (MP). The present study was carried out to investigate the anti-inflammatory and hepatoprotective effects of these three extracts in rats. The results indicated that extracts of HC, HD and MP possess anti-inflammatory activity, and that MP has the greatest inhibition against carrageenan-induced paw edema. In the hepatoprotective study, results indicated that the three plant extracts significantly reduced the acute elevation of serum glutamate oxalate transaminase (sGOT) and serum glutamate pyruvate transaminase (sGPT) concentration, and alleviated the degree of liver damage 24 hours after the intraperitoneal administration of hepatotoxins.

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Year:  2002        PMID: 12230011     DOI: 10.1142/S0192415X02000405

Source DB:  PubMed          Journal:  Am J Chin Med        ISSN: 0192-415X            Impact factor:   4.667


  13 in total

1.  Novel cyclotides from Hedyotis diffusa induce apoptosis and inhibit proliferation and migration of prostate cancer cells.

Authors:  Enping Hu; Dongguo Wang; Jiayu Chen; Xiulin Tao
Journal:  Int J Clin Exp Med       Date:  2015-03-15

2.  Chemical constituents from Oldenlandia corymbosa L. of Thai origin.

Authors:  Pawadee Noiarsa; Somsak Ruchirawat; Hideaki Otsuka; Tripetch Kanchanapoom
Journal:  J Nat Med       Date:  2007-12-05       Impact factor: 2.343

3.  Hedyotis diffusa Willd inhibits colorectal cancer growth in vivo via inhibition of STAT3 signaling pathway.

Authors:  Qiaoyan Cai; Jiumao Lin; Lihui Wei; Ling Zhang; Lili Wang; Youzhi Zhan; Jianwei Zeng; Wei Xu; Aling Shen; Zhenfeng Hong; Jun Peng
Journal:  Int J Mol Sci       Date:  2012-05-18       Impact factor: 6.208

4.  Effects of Mollugo pentaphylla extract on monosodium urate crystal-induced gouty arthritis in mice.

Authors:  Yun Mi Lee; Eun-Jung Shon; Ohn Soon Kim; Dong-Seon Kim
Journal:  BMC Complement Altern Med       Date:  2017-09-06       Impact factor: 3.659

5.  Extraction, Characterization, Antioxidant, and Immunostimulatory Activities of Polysaccharides from Hedyotis corymbosa.

Authors:  Li-Mei Lin; Su-Hui Xiong; Ling-Jia Zhao; Jie Tang; Zhi-Min Zhang; Ya-Mei Li; Tao Zheng; Bo-Hou Xia
Journal:  Evid Based Complement Alternat Med       Date:  2018-11-14       Impact factor: 2.629

6.  Discovery of the Potential Biomarkers for Discrimination between Hedyotis diffusa and Hedyotis corymbosa by UPLC-QTOF/MS Metabolome Analysis.

Authors:  Yaru Wang; Cuizhu Wang; Hongqiang Lin; Yunhe Liu; Yameng Li; Yan Zhao; Pingya Li; Jinping Liu
Journal:  Molecules       Date:  2018-06-25       Impact factor: 4.411

7.  Mitigation of Aflatoxin B1 Hepatoxicity by Dietary Hedyotis diffusa Is Associated with Activation of NRF2/ARE Signaling in Chicks.

Authors:  Ling Zhao; Jiang Deng; Zi-Jian Xu; Wan-Po Zhang; Mahmoud Mohamed Khalil; Niel Alexander Karrow; Lv-Hui Sun
Journal:  Antioxidants (Basel)       Date:  2021-05-30

8.  Chemical Profiles and Protective Effect of Hedyotis diffusa Willd in Lipopolysaccharide-Induced Renal Inflammation Mice.

Authors:  Jian-Hong Ye; Meng-Hua Liu; Xu-Lin Zhang; Jing-Yu He
Journal:  Int J Mol Sci       Date:  2015-11-13       Impact factor: 5.923

9.  A Network Pharmacology Approach to Uncover the Multiple Mechanisms of Hedyotis diffusa Willd. on Colorectal Cancer.

Authors:  Xinkui Liu; Jiarui Wu; Dan Zhang; Kaihuan Wang; Xiaojiao Duan; Xiaomeng Zhang
Journal:  Evid Based Complement Alternat Med       Date:  2018-02-12       Impact factor: 2.629

Review 10.  Anticancer Plants: A Review of the Active Phytochemicals, Applications in Animal Models, and Regulatory Aspects.

Authors:  Tariq Khan; Muhammad Ali; Ajmal Khan; Parveen Nisar; Sohail Ahmad Jan; Shakeeb Afridi; Zabta Khan Shinwari
Journal:  Biomolecules       Date:  2019-12-27
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