| Literature DB >> 12227808 |
Ke-Gang Liu1, Shi Yan, Yu-Lin Wu, Zhu-Jun Yao.
Abstract
A new route to Neu5Ac methyl ester (23) with a readily available sugar D-glucono-delta-lactone as starting material has been developed. A diastereoselective propargylation of alpha-acetamino aldehyde and a subsequent KMnO(4) oxidation of the terminal alkyne served as the key steps.Entities:
Year: 2002 PMID： 12227808 DOI： 10.1021/jo026056o
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354