Literature DB >> 12208533

Test-retest reliability of the somatosensory blink reflex and its inhibition.

Magne Arve Flaten1.   

Abstract

Prepulse inhibition (PPI) involves inhibition of the blink reflex by a weak stimulus or prepulse presented immediately prior to the blink reflex-eliciting stimulus. Ten subjects were tested for PPI two times each day with a 60 min pause between tests, for 4 days spaced 1 week apart. Both the somatosensory blink reflex and its inhibition by an acoustic prepulse, presented 50, 100, 200, 400 and 800 ms prior to the reflex-eliciting stimulus, were investigated. The results showed very high reliability for the blink reflex across all eight tests (Chronbach's alpha=0.98). Inhibition of the reflex by a prepulse displayed alphas of >0.94, and percentage of PPI also displayed significant reliability. Blink latency also displayed high reliability. In sum, the reliability of the somatosensory blink reflex and its inhibition is very high.

Mesh:

Year:  2002        PMID: 12208533     DOI: 10.1016/s0167-8760(02)00034-x

Source DB:  PubMed          Journal:  Int J Psychophysiol        ISSN: 0167-8760            Impact factor:   2.997


  11 in total

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Journal:  Neuroreport       Date:  2013-08-07       Impact factor: 1.837

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Authors:  Peggy Postma; Jeffrey A Gray; Tonmoy Sharma; Mark Geyer; Ravi Mehrotra; Mrigen Das; Elizabeth Zachariah; Melissa Hines; Steven C R Williams; Veena Kumari
Journal:  Psychopharmacology (Berl)       Date:  2006-02-02       Impact factor: 4.530

Review 3.  Neurophysiological endophenotypes of schizophrenia: the viability of selected candidate measures.

Authors:  Bruce I Turetsky; Monica E Calkins; Gregory A Light; Ann Olincy; Allen D Radant; Neal R Swerdlow
Journal:  Schizophr Bull       Date:  2006-11-29       Impact factor: 9.306

4.  The association of schizophrenia risk D-amino acid oxidase polymorphisms with sensorimotor gating, working memory and personality in healthy males.

Authors:  Panos Roussos; Stella G Giakoumaki; Eva Adamaki; Anastasios Georgakopoulos; Georgakopoulos Anastasios; Nikos K Robakis; Robakis K Nikos; Panos Bitsios
Journal:  Neuropsychopharmacology       Date:  2011-04-06       Impact factor: 7.853

5.  Prospective longitudinal assessment of sensorimotor gating as a risk/resiliency factor for posttraumatic stress disorder.

Authors:  Mark A Geyer; Victoria B Risbrough; Dean T Acheson; Dewleen G Baker; Caroline M Nievergelt; Kate A Yurgil
Journal:  Neuropsychopharmacology       Date:  2022-10-03       Impact factor: 8.294

Review 6.  Realistic expectations of prepulse inhibition in translational models for schizophrenia research.

Authors:  Neal R Swerdlow; Martin Weber; Ying Qu; Gregory A Light; David L Braff
Journal:  Psychopharmacology (Berl)       Date:  2008-06-21       Impact factor: 4.530

7.  Prepulse inhibition in fragile X syndrome: feasibility, reliability, and implications for treatment.

Authors:  David Hessl; Elizabeth Berry-Kravis; Lisa Cordeiro; Jennifer Yuhas; Edward M Ornitz; Aaron Campbell; Elizabeth Chruscinski; Crystal Hervey; James M Long; Randi J Hagerman
Journal:  Am J Med Genet B Neuropsychiatr Genet       Date:  2009-06-05       Impact factor: 3.568

8.  Reduced Prepulse Inhibition as a Biomarker of Schizophrenia.

Authors:  Auxiliadora Mena; Juan C Ruiz-Salas; Andrea Puentes; Inmaculada Dorado; Miguel Ruiz-Veguilla; Luis G De la Casa
Journal:  Front Behav Neurosci       Date:  2016-10-18       Impact factor: 3.558

9.  Prepulse inhibition of auditory change-related cortical responses.

Authors:  Koji Inui; Aki Tsuruhara; Minori Kodaira; Eishi Motomura; Hisashi Tanii; Makoto Nishihara; Sumru Keceli; Ryusuke Kakigi
Journal:  BMC Neurosci       Date:  2012-10-31       Impact factor: 3.288

Review 10.  Therapeutic Potential of Selectively Targeting the α2C-Adrenoceptor in Cognition, Depression, and Schizophrenia-New Developments and Future Perspective.

Authors:  Madeleine Monique Uys; Mohammed Shahid; Brian Herbert Harvey
Journal:  Front Psychiatry       Date:  2017-08-14       Impact factor: 4.157

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