Literature DB >> 12203646

Adhesion Forces between Lewis(X) Determinant Antigens as Measured by Atomic Force Microscopy.

C Tromas1, J Rojo, J M de la Fuente, A G Barrientos, R García, S Penadés.   

Abstract

The adhesion forces between individual molecules of Lewis(X) trisaccharide antigen (Le(X) ) have been measured in water and in calcium solution by using atomic force microscopy (AFM, see graph). These results demonstrate the self-recognition capability of this antigen, and reinforce the hypothesis that carbohydrate-carbohydrate interaction could be considered as the first step in the cell-adhesion process in nature.
Copyright © 2001 WILEY-VCH Verlag GmbH, Weinheim, Fed. Rep. of Germany.

Entities:  

Keywords:  antigens; atomic force microscopy; carbohydrates; gold; noncovalent interactions

Year:  2001        PMID： 12203646     DOI： 10.1002/1521-3773(20010817)40:16<3052::AID-ANIE3052>3.0.CO;2-Q

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


  30 in total

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Review 7.  Understanding carbohydrate-carbohydrate interactions by means of glyconanotechnology.

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