| Literature DB >> 12201725 |
Chen Li1, James B Gloer, Donald T Wicklow, Patrick F Dowd.
Abstract
[structure: see text] Two novel antiinsectan indole diterpenoids, thiersinines A (1) and B (2), along with seven known paxilline-type compounds, were isolated from organic extracts of a new Penicillium species (P. thiersii NRRL 28147). The structures of 1 and 2 were determined by analysis of 2D NMR data. Thiersinines A and B possess a unique spirocyclic subunit that is unprecedented in previously known compounds of this class. Both compounds exhibit potent activity against the fall armyworm (Spodoptera frugiperda).Entities:
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Year: 2002 PMID: 12201725 DOI: 10.1021/ol026424a
Source DB: PubMed Journal: Org Lett ISSN: 1523-7052 Impact factor: 6.005