Literature DB >> 12196948

A new one-pot three-component condensation reaction for the synthesis of 2,3,4,6-tetrasubstituted pyridines.

Mark C Bagley1, James W Dale, Justin Bower.   

Abstract

The one-pot three-component condensation of a beta-ketoester, ammonia and an alkynone in the presence of a Brønsted or Lewis acid or Amberlyst 15 ion exchange resin provided 2,3,6-trisubstituted or 2,3,4,6-tetrasubstituted pyridines directly in good yield and with total regiocontrol.

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Year:  2002        PMID： 12196948     DOI： 10.1039/b203900a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  8 in total

1.  A green one-pot three-component cascade reaction: the synthesis of 2-amino-5,8-dihydro-3H-pyrido[2,3-D]pyrimidin-4-ones in aqueous medium.

Authors:  Ahmad Shaabani; Heshmatollah Sepahvand; Mahmoud Borjian Boroujeni; Mohammad Tayeb Faroghi
Journal:  Mol Divers       Date:  2017-01-12       Impact factor: 2.943

Review 2.  Transition metal-mediated synthesis of monocyclic aromatic heterocycles.

Authors:  Anton V Gulevich; Alexander S Dudnik; Natalia Chernyak; Vladimir Gevorgyan
Journal:  Chem Rev       Date:  2013-01-10       Impact factor: 60.622

3.  Efficient synthesis of functionalized spiro[indoline-3,4'-pyrrolo[3,4-b]pyridines] via one-pot three-component reaction.

Authors:  Chao Wang; Yan-Hong Jiang; Chao-Guo Yan
Journal:  Mol Divers       Date:  2014-07-31       Impact factor: 2.943

4.  Total synthesis and complete structural assignment of thiocillin I.

Authors:  Virender S Aulakh; Marco A Ciufolini
Journal:  J Am Chem Soc       Date:  2011-03-29       Impact factor: 15.419

5.  Reagent-controlled regiodivergent intermolecular cyclization of 2-aminobenzothiazoles with β-ketoesters and β-ketoamides.

Authors:  Irwan Iskandar Roslan; Kian-Hong Ng; Gaik-Khuan Chuah; Stephan Jaenicke
Journal:  Beilstein J Org Chem       Date:  2017-12-18       Impact factor: 2.883

6.  Synthesis of indeno-[1,2-b]-quinoline-9,11(6H,10H)-dione and 7,7-dimethyl-10-aryl-7,8-dihydro-5H-indeno[1,2-b]quinoline-9,11(6H,10H)-dione derivatives in presence of heterogeneous Cu/zeolite-Y as a catalyst.

Authors:  Shankar D Dhengale; Chandrashekhar V Rode; Govind B Kolekar; Prashant V Anbhule
Journal:  RSC Adv       Date:  2022-01-13       Impact factor: 3.361

7.  Synthesis of functionalized spiro[indoline-3,4'-pyridines] and spiro[indoline-3,4'-pyridinones] via one-pot four-component reactions.

Authors:  Li-Juan Zhang; Qun Wu; Jing Sun; Chao-Guo Yan
Journal:  Beilstein J Org Chem       Date:  2013-05-02       Impact factor: 2.883

8.  Facile synthesis of functionalized tetrahydroquinolines via domino Povarov reactions of arylamines, methyl propiolate and aromatic aldehydes.

Authors:  Jing Sun; Hong Gao; Qun Wu; Chao-Guo Yan
Journal:  Beilstein J Org Chem       Date:  2012-10-26       Impact factor: 2.883
  8 in total

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