Literature DB >> 12195612

Why do you prescribe methylprednisolone for acute spinal cord injury? A Canadian perspective and a position statement.

R J Hurlbert1, R Moulton.   

Abstract

OBJECTIVE: To determine the practice patterns for methylprednisolone administration for patients with acute spinal cord injury (SCI) within the spinal surgery community across Canada, and the reasons behind these patterns.
METHODS: Canadian neurological and orthopedic spine surgeons were surveyed at their respective annual meetings with a questionnaire asking seven questions with respect to their practice standards.
RESULTS: Sixty surgeons completed the survey representing approximately two-thirds of surgeons treating acute SCI within Canada. The NASCIS III dosing regimen is the most commonly prescribed steroid protocol. However, one-quarter of surgeons do not administer steroids at all. Of those who administer methylprednisolone, most do so because of peer pressure or out of fear of litigation.
CONCLUSIONS: The vast majority of spine surgeons in Canada either do not prescribe methylprednisolone for acute SCI, or do so for what might be considered the wrong reasons. These results demonstrate the need for an evidence-based practice guideline. The Canadian Spine Society and the Canadian Neurosurgical Society fully endorse the recommendations of the steroid task force (see preceding paper).

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Year:  2002        PMID: 12195612     DOI: 10.1017/s0317167100002006

Source DB:  PubMed          Journal:  Can J Neurol Sci        ISSN: 0317-1671            Impact factor:   2.104


  15 in total

1.  Cochrane in CORR1: Steroids for Acute Spinal Cord Injury (Review).

Authors:  Nathan Evaniew; Marcel Dvorak
Journal:  Clin Orthop Relat Res       Date:  2016-01       Impact factor: 4.176

2.  High dose methylprednisolone in the immediate management of acute, blunt spinal cord injury: what is the current practice in emergency departments, spinal units, and neurosurgical units in the UK?

Authors:  A E Frampton; C A Eynon
Journal:  Emerg Med J       Date:  2006-07       Impact factor: 2.740

Review 3.  [Prehospital management of spinal cord injuries].

Authors:  M Bernhard; A Gries; P Kremer; A Martin-Villalba; B W Böttiger
Journal:  Anaesthesist       Date:  2005-04       Impact factor: 1.041

Review 4.  Spinal cord injury II: Prognostic indicators, standards of care, and clinical trials.

Authors:  Aubrey A Webb; Sybil Ngan; David Fowler
Journal:  Can Vet J       Date:  2010-06       Impact factor: 1.008

Review 5.  A review: the role of high dose methylprednisolone in spinal cord trauma in children.

Authors:  Janine N Pettiford; Jai Bikhchandani; Daniel J Ostlie; Shawn D St Peter; Ronald J Sharp; David Juang
Journal:  Pediatr Surg Int       Date:  2011-10-13       Impact factor: 1.827

6.  Quantitative iTRAQ proteomics reveal the proteome profiles of bone marrow mesenchymal stem cells after cocultures with Schwann cells in vitro.

Authors:  Han Ding; Ang Li; Chao Sun; Jianping Zhang; Jun Shang; Haoshuai Tang; Junjin Li; Min Wang; Xiaohong Kong; Zhijian Wei; Shiqing Feng
Journal:  Ann Transl Med       Date:  2022-09

Review 7.  Cervical spine injuries in American football.

Authors:  Jeffrey A Rihn; David T Anderson; Kathleen Lamb; Peter F Deluca; Ahmed Bata; Paul A Marchetto; Nuno Neves; Alexander R Vaccaro
Journal:  Sports Med       Date:  2009       Impact factor: 11.136

8.  Intramedullary lesion expansion on magnetic resonance imaging in patients with motor complete cervical spinal cord injury.

Authors:  Bizhan Aarabi; J Marc Simard; Joseph A Kufera; Melvin Alexander; Katie M Zacherl; Stuart E Mirvis; Kathirkamanthan Shanmuganathan; Gary Schwartzbauer; Christopher M Maulucci; Justin Slavin; Khawar Ali; Jennifer Massetti; Howard M Eisenberg
Journal:  J Neurosurg Spine       Date:  2012-07-13

9.  Immunoglobulin G (IgG) attenuates neuroinflammation and improves neurobehavioral recovery after cervical spinal cord injury.

Authors:  Dung Hoang Nguyen; Newton Cho; Kajana Satkunendrarajah; James W Austin; Jian Wang; Michael G Fehlings
Journal:  J Neuroinflammation       Date:  2012-09-21       Impact factor: 8.322

10.  Methylprednisolone for the Treatment of Patients with Acute Spinal Cord Injuries: A Propensity Score-Matched Cohort Study from a Canadian Multi-Center Spinal Cord Injury Registry.

Authors:  Nathan Evaniew; Vanessa K Noonan; Nader Fallah; Brian K Kwon; Carly S Rivers; Henry Ahn; Christopher S Bailey; Sean D Christie; Daryl R Fourney; R John Hurlbert; A G Linassi; Michael G Fehlings; Marcel F Dvorak
Journal:  J Neurotrauma       Date:  2015-07-17       Impact factor: 5.269

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