Literature DB >> 15682329

[Prehospital management of spinal cord injuries].

M Bernhard1, A Gries, P Kremer, A Martin-Villalba, B W Böttiger.   

Abstract

In both the United States and Europe about 10,000 patients suffer from spinal cord injury (SCI) each year and 20% die before being admitted to hospital. Prehospital management of SCI is very important since 25% of SCI damage may occur after the initial event. Emergency treatment includes examination of the patient, spinal immobilization, careful airway management, cardiovascular stabilization (maintenance of mean arterial blood pressure above 90 mmHg) and glucose levels within the normal range. From an evidence-based point of view, it is still not known whether additional specific therapy is useful and studies have not convincingly demonstrated that methylprednisolone (MPS) or other substances have clinically important benefits. Recently published statements from the US do not support the therapeutic use of MPS in patients suffering from SCI in the prehospital setting. Moreover, it is not known whether hypothermia or any other pharmacological interventions have beneficial effects. Networks for clinical studies in SCI patients should be established as a basic requirement for further improvement in outcome in these patients.

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Year:  2005        PMID: 15682329     DOI: 10.1007/s00101-005-0807-4

Source DB:  PubMed          Journal:  Anaesthesist        ISSN: 0003-2417            Impact factor:   1.041


  115 in total

1.  Effects of cervical spine immobilization technique and laryngoscope blade selection on an unstable cervical spine in a cadaver model of intubation.

Authors:  M C Gerling; D P Davis; R S Hamilton; G F Morris; G M Vilke; S R Garfin; S R Hayden
Journal:  Ann Emerg Med       Date:  2000-10       Impact factor: 5.721

Review 2.  Neurotrophic factors, gene therapy, and neural stem cells for spinal cord repair.

Authors:  Armin Blesch; Paul Lu; Mark H Tuszynski
Journal:  Brain Res Bull       Date:  2002-04       Impact factor: 4.077

3.  Prehospital care of the multiply injured patient: the challenge of figuring out what works.

Authors:  Roger J Lewis
Journal:  JAMA       Date:  2004-03-17       Impact factor: 56.272

4.  Neurotrophism without neurotropism: BDNF promotes survival but not growth of lesioned corticospinal neurons.

Authors:  P Lu; A Blesch; M H Tuszynski
Journal:  J Comp Neurol       Date:  2001-08-06       Impact factor: 3.215

5.  A critical appraisal of the reporting of the National Acute Spinal Cord Injury Studies (II and III) of methylprednisolone in acute spinal cord injury.

Authors:  W P Coleman; D Benzel; D W Cahill; T Ducker; F Geisler; B Green; M R Gropper; J Goffin; P W Madsen; D J Maiman; S L Ondra; M Rosner; R C Sasso; G R Trost; S Zeidman
Journal:  J Spinal Disord       Date:  2000-06

6.  Experimental treatments of acute spinal cord injury.

Authors:  T B Ducker; H F Hamit
Journal:  J Neurosurg       Date:  1969-06       Impact factor: 5.115

7.  Agmatine improves locomotor function and reduces tissue damage following spinal cord injury.

Authors:  C G Yu; A E Marcillo; C A Fairbanks; G L Wilcox; R P Yezierski
Journal:  Neuroreport       Date:  2000-09-28       Impact factor: 1.837

8.  Causes and costs of spinal cord injury in the United States.

Authors:  M J DeVivo
Journal:  Spinal Cord       Date:  1997-12       Impact factor: 2.772

9.  A phase I trial of naloxone treatment in acute spinal cord injury.

Authors:  E S Flamm; W Young; W F Collins; J Piepmeier; G L Clifton; B Fischer
Journal:  J Neurosurg       Date:  1985-09       Impact factor: 5.115

10.  Apoptosis after traumatic human spinal cord injury.

Authors:  E Emery; P Aldana; M B Bunge; W Puckett; A Srinivasan; R W Keane; J Bethea; A D Levi
Journal:  J Neurosurg       Date:  1998-12       Impact factor: 5.115

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  2 in total

Review 1.  [The preclinical care of polytraumatized patients].

Authors:  J Döhnert; B Auerbach; W Wyrwich; C E Heyde
Journal:  Orthopade       Date:  2005-09       Impact factor: 1.087

Review 2.  [Treatment of polytrauma in the intensive care unit].

Authors:  V Mann; S Mann; G Szalay; M Hirschburger; R Röhrig; C Dictus; T Wurmb; M A Weigand; M Bernhard
Journal:  Anaesthesist       Date:  2010-08       Impact factor: 1.041

  2 in total

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