| Literature DB >> 12193035 |
Nicola Borbone1, Simona De Marino, Maria Iorizzi, Franco Zollo, Cecile Debitus, Giuseppe Esposito, Teresa Iuvone.
Abstract
Four new steroidal alkaloids, plakinamine G (1), plakinamine H (2), 4alpha-hydroxydemethylplakinamine B (3), and tetrahydroplakinamine A (4), along with three known compounds, were isolated from the marine sponge Corticium sp. The structures of these metabolites were elucidated largely by 1D and 2D NMR methods and accurate mass measurements (HR-EIMS). Compounds 1, 2, and 4 show significant in vitro cytotoxicity.Entities:
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Year: 2002 PMID： 12193035 DOI： 10.1021/np020027r
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050