Literature DB >> 12193025

5-hydroxytryptamine-derived alkaloids from two marine sponges of the genus Hyrtios.

Mostafa Salmoun1, Christine Devijver, Désiré Daloze, Jean-Claude Braekman, Rob W M van Soest.   

Abstract

Indonesian specimens of the marine sponges Hyrtios erectus and H. reticulatus were found to contain 5-hydroxytryptamine-derived alkaloids. Their structures were determined on the basis of their spectral properties. H. erectus contained hyrtiosulawesine (4), a new beta-carboline alkaloid, together with the already known alkaloids 5-hydroxyindole-3-carbaldehyde (1), hyrtiosin B (2), and 5-hydroxy-3-(2-hydroxyethyl)indole (3). H. reticulatus contained the novel derivative 1,6-dihydroxy-1,2,3,4-tetrahydro-beta-carboline (11) together with serotonin (5), 6-hydroxy-1-methyl-1,2,3,4-tetrahydro-beta-carboline (7), and 6-hydroxy-3,4-dihydro-1-oxo-beta-carboline (9).

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Year:  2002        PMID： 12193025     DOI： 10.1021/np020009+

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  15 in total

Review 1.  Carboxylesterase inhibitors.

Authors:  M Jason Hatfield; Philip M Potter
Journal:  Expert Opin Ther Pat       Date:  2011-05-24       Impact factor: 6.674

2.  Two new indole derivatives from a marine sponge Ircinia sp. collected at Iriomote Island.

Authors:  Delfly B Abdjul; Hiroyuki Yamazaki; Kazuyo Ukai; Michio Namikoshi
Journal:  J Nat Med       Date:  2015-02-24       Impact factor: 2.343

3.  A beta-carboline alkaloid from the Papua New Guinea marine sponge hyrtios reticulatus.

Authors:  Wayne D Inman; Walter M Bray; Nadine C Gassner; R Scott Lokey; Karen Tenney; Young Yongchun Shen; Karen Tendyke; Ted Suh; Phillip Crews
Journal:  J Nat Prod       Date:  2010-02-26       Impact factor: 4.050

4.  Inhibitory effect of a callophycin A derivative on iNOS expression via inhibition of Akt in lipopolysaccharide-stimulated RAW 264.7 cells.

Authors:  Eun-Jung Park; Li Shen; Dianqing Sun; John M Pezzuto
Journal:  J Nat Prod       Date:  2013-12-03       Impact factor: 4.050

Review 5.  Neural versus alternative integrative systems: molecular insights into origins of neurotransmitters.

Authors:  Leonid L Moroz; Daria Y Romanova; Andrea B Kohn
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2021-02-08       Impact factor: 6.237

6.  Hainanerectamines A-C, alkaloids from the Hainan sponge Hyrtios erecta.

Authors:  Wen-Fei He; Duo-Qing Xue; Li-Gong Yao; Jing-Ya Li; Jia Li; Yue-Wei Guo
Journal:  Mar Drugs       Date:  2014-06-30       Impact factor: 5.118

7.  Antiproliferative Scalarane-Based Metabolites from the Red Sea Sponge Hyrtios erectus.

Authors:  Sameh S Elhady; Ahmed M Al-Abd; Ali M El-Halawany; Abdulrahman M Alahdal; Hashim A Hassanean; Safwat A Ahmed
Journal:  Mar Drugs       Date:  2016-07-08       Impact factor: 5.118

8.  Antiproliferative and Proapoptotic Activities of Marine Sponge Hyrtios erectus Extract on Breast Carcinoma Cell Line (MCF-7).

Authors:  Ramachandran Muthiyan; Balwin Nambikkairaj; Nilkamal Mahanta; Titus Immanuel; Rahul Shubhra Mandal; Kubendiran Kumaran; Arun Kumar De
Journal:  Pharmacogn Mag       Date:  2017-04-07       Impact factor: 1.085

9.  Merosesquiterpene Congeners from the Australian Sponge Hyrtios digitatus as Potential Drug Leads for Atherosclerosis Disease.

Authors:  Huda A Wahab; Ngoc B Pham; Tengku S Tengku Muhammad; John N A Hooper; Ronald J Quinn
Journal:  Mar Drugs       Date:  2016-12-27       Impact factor: 5.118

10.  Bioactive compounds from the Red Sea marine sponge Hyrtios species.

Authors:  Diaa T A Youssef; Lamiaa A Shaala; Hani Z Asfour
Journal:  Mar Drugs       Date:  2013-03-28       Impact factor: 5.118
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