Literature DB >> 12191638

DNA methylation and genomic imprinting: insights from cancer into epigenetic mechanisms.

Andrew P Feinberg1, Hengmi Cui, Rolf Ohlsson.   

Abstract

Since the discovery of epigenetic alterations in cancer 20 years ago by Feinberg and Vogelstein, a variety of such alterations have been found, including global hypomethylation, gene hypomethylation and hypermethylation, and loss of imprinting (LOI). LOI may precede the development of cancer and may thus serve as a common marker for risk, but also as a model for understanding the developmental mechanism for normal imprinting.

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Year:  2002        PMID: 12191638     DOI: 10.1016/s1044-579x(02)00059-7

Source DB:  PubMed          Journal:  Semin Cancer Biol        ISSN: 1044-579X            Impact factor:   15.707


  45 in total

1.  Aberrant methylation of the maspin promoter is an early event in human breast cancer.

Authors:  Bernard W Futscher; Megan M O'Meara; Christina J Kim; Margaret A Rennels; Di Lu; Lynn M Gruman; Richard E B Seftor; Mary J C Hendrix; Frederick E Domann
Journal:  Neoplasia       Date:  2004 Jul-Aug       Impact factor: 5.715

Review 2.  Epigenetic effects of endocrine-disrupting chemicals on female reproduction: an ovarian perspective.

Authors:  Aparna Mahakali Zama; Mehmet Uzumcu
Journal:  Front Neuroendocrinol       Date:  2010-07-04       Impact factor: 8.606

3.  Prostaglandin E₂ increases fibroblast gene-specific and global DNA methylation via increased DNA methyltransferase expression.

Authors:  Steven K Huang; Anne M Scruggs; Jake Donaghy; Richard C McEachin; Aaron S Fisher; Bruce C Richardson; Marc Peters-Golden
Journal:  FASEB J       Date:  2012-05-29       Impact factor: 5.191

Review 4.  The new field of epigenomics: implications for cancer and other common disease research.

Authors:  H T Bjornsson; H Cui; D Gius; M D Fallin; A P Feinberg
Journal:  Cold Spring Harb Symp Quant Biol       Date:  2004

5.  A complex deoxyribonucleic acid looping configuration associated with the silencing of the maternal Igf2 allele.

Authors:  Xinwen Qiu; Thanh H Vu; Qiucheng Lu; Jian Qun Ling; Tao Li; Aiju Hou; Shu Kui Wang; Hui Ling Chen; Ji Fan Hu; Andrew R Hoffman
Journal:  Mol Endocrinol       Date:  2008-03-20

Review 6.  Epigenetics, aging, and autoimmunity.

Authors:  Raymond L Yung; Annabelle Julius
Journal:  Autoimmunity       Date:  2008-05       Impact factor: 2.815

7.  Deficiency of Rbbp1/Arid4a and Rbbp1l1/Arid4b alters epigenetic modifications and suppresses an imprinting defect in the PWS/AS domain.

Authors:  Mei-Yi Wu; Ting-Fen Tsai; Arthur L Beaudet
Journal:  Genes Dev       Date:  2006-10-15       Impact factor: 11.361

8.  The histone demethylase Dmel\Kdm4A controls genes required for life span and male-specific sex determination in Drosophila.

Authors:  Meridith T Lorbeck; Neetu Singh; Ashley Zervos; Madhusmita Dhatta; Maria Lapchenko; Chen Yang; Felice Elefant
Journal:  Gene       Date:  2010-01-15       Impact factor: 3.688

9.  Quantitative analysis of associations between DNA hypermethylation, hypomethylation, and DNMT RNA levels in ovarian tumors.

Authors:  M Ehrlich; C B Woods; M C Yu; L Dubeau; F Yang; M Campan; D J Weisenberger; Ti Long; B Youn; E S Fiala; P W Laird
Journal:  Oncogene       Date:  2006-04-27       Impact factor: 9.867

10.  DNA methylation in circulating tumour DNA as a biomarker for cancer.

Authors:  Ruth E Board; Lucy Knight; Alastair Greystoke; Fiona H Blackhall; Andrew Hughes; Caroline Dive; Malcolm Ranson
Journal:  Biomark Insights       Date:  2008-01-25
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