| Literature DB >> 12189451 |
S-J Wang1, J-L Lan, J-L Lan, D-Y Chen, Y-H Chen, T-Y Hsieh, W-Y Lin.
Abstract
Progressive systemic sclerosis (PSS) may involve any portion of the gastrointestinal tract, including the colon. Constipation is common in patients with PSS. Cisapride, a benzamide derivative, is a potentially useful agent in the treatment of chronic idiopathic constipation. The effect of cisapride on colonic transit was evaluated in 16 PSS patients by a radionuclide colonic transit method. Each patient received cisapride orally three times a day for a week. The results showed acceleration in colonic transit in response to cisapride. We conclude that cisapride is effective in the treatment of constipation in patients with PSS.Entities:
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Year: 2002 PMID： 12189451 DOI： 10.1007/s100670200072
Source DB: PubMed Journal: Clin Rheumatol ISSN： 0770-3198 Impact factor: 2.980