| Literature DB >> 12188661 |
Jorge Sánchez-Quesada1, Markus P Isler, M Reza Ghadiri.
Abstract
A selective heteromeric supramolecular assembly process is devised to create functional single channels of altered ion conductance, charge selectivity, and rectification. The hollow transmembrane tubular structure produced spontaneously from the self-assembly of cyclic-d,l-alpha-peptides in lipid bilayers is modified by designer cyclic peptide "cap" subunits that bind site-selectively at the mouth of the channel assembly.Entities:
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Year: 2002 PMID： 12188661 DOI： 10.1021/ja025983+
Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419