[Subjective Quality of Life in opiate-dependent patients before admission after six months and one-year participation in methadone program].

The aim of this study was to compare a subjective Quality of Life (QoL) assessment before, after six and twelve months of participating in methadone program. There were included 61 patients (39 males and 22 females). The SF-36 questionnaire was used. We found that in our patients before admission to methadone program QoL was extremely low. After six-months participation in substitution therapy QoL increased significantly in seven from eight subscales of SF-36. During next six months QoL unexpectedly decrease, but not to prior level. There were not significant differences in QoL between men and women although men beneficiated from methadone program more than women. In our study HIV seropositivity hadn't influence on QoL.