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Literature DB >> 12182609

A simple and advantageous protocol for the oxidation of alcohols with O-iodoxybenzoic acid (IBX).

Abstract

[reaction: see text] An efficient, user-friendly procedure for the oxidation of alcohols using IBX is described. Simply heating a solution of the alcohol in the presence of suspended IBX followed by filtration and removal of the solvent gives excellent yields of the corresponding carbonyl compounds. We illustrate this procedure with a panel of primary and secondary alcohol substrates and note that it allows recycling and reuse of the oxidant.

Entities: Chemical

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Year: 2002 PMID： 12182609 DOI： 10.1021/ol026427n

Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005

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Cited

31 in total

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A simple and advantageous protocol for the oxidation of alcohols with O-iodoxybenzoic acid (IBX).

1. Enantiospecific Synthesis and Biological Investigations of a Nuphar Alkaloid: Proposed Structure of a Castoreum Component.

2. Improved synthesis of 15-deoxyspergualin analogs using the Ugi multi-component reaction.

3. An Enantioselective Approach to the Securinega Alkaloids: The Total Synthesis of (+)-Norsecurinine and (+)-Allonorsecurinine.

4. A synthetic entry to pladienolide B and FD-895.

5. Synthesis of pluraflavin A "aglycone".

Review 6. Chemistry of polyvalent iodine.

7. The Scent Chemistry of Heliconius Wing Androconia.

8. Structure of FD-895 revealed through total synthesis.

9. Studies of stereocontrolled allylation reactions for the total synthesis of phorboxazole A.

10. A concise synthesis of the cortistatin core.