Literature DB >> 12180959

Near real time in vivo fibre optic confocal microscopy: sub-cellular structure resolved.

K B Sung1, C Liang, M Descour, T Collier, M Follen, A Malpica, R Richards-Kortum.   

Abstract

We have built a fibre optic confocal reflectance microscope capable of imaging biological tissue in near real time. The measured lateral resolution is 3 micro m and axial resolution is 6 micro m. Images of epithelial cells, excised tissue biopsies, and the human lip in vivo have been obtained at 15 frames s-1. Both cell morphology and tissue architecture can be appreciated from images obtained with this microscope. This device has the potential to enable reflected light confocal imaging of internal organs for in situ detection of pathology.

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Year:  2002        PMID： 12180959     DOI： 10.1046/j.1365-2818.2002.01049.x

Source DB:  PubMed          Journal:  J Microsc        ISSN： 0022-2720            Impact factor:   1.758


  11 in total

1.  In vivo imaging of oral neoplasia using a miniaturized fiber optic confocal reflectance microscope.

Authors:  Kristen C Maitland; Ann M Gillenwater; Michelle D Williams; Adel K El-Naggar; Michael R Descour; Rebecca R Richards-Kortum
Journal:  Oral Oncol       Date:  2008-04-08       Impact factor: 5.337

2.  Bessel-beam illumination in dual-axis confocal microscopy mitigates resolution degradation caused by refractive heterogeneities.

Authors:  Ye Chen; Adam Glaser; Jonathan T C Liu
Journal:  J Biophotonics       Date:  2016-09-26       Impact factor: 3.207

Review 3.  Trends in fluorescence image-guided surgery for gliomas.

Authors:  Jonathan T C Liu; Daphne Meza; Nader Sanai
Journal:  Neurosurgery       Date:  2014-07       Impact factor: 4.654

Review 4.  Confocal endomicroscopy: instrumentation and medical applications.

Authors:  Joey M Jabbour; Meagan A Saldua; Joel N Bixler; Kristen C Maitland
Journal:  Ann Biomed Eng       Date:  2011-10-13       Impact factor: 3.934

Review 5.  Optical imaging for cervical cancer detection: solutions for a continuing global problem.

Authors:  Nadhi Thekkek; Rebecca Richards-Kortum
Journal:  Nat Rev Cancer       Date:  2008-09       Impact factor: 60.716

6.  Miniature in vivo MEMS-based line-scanned dual-axis confocal microscope for point-of-care pathology.

Authors:  C Yin; A K Glaser; S Y Leigh; Y Chen; L Wei; P C S Pillai; M C Rosenberg; S Abeytunge; G Peterson; C Glazowski; N Sanai; M J Mandella; M Rajadhyaksha; J T C Liu
Journal:  Biomed Opt Express       Date:  2016-01-05       Impact factor: 3.732

7.  Use of high-resolution confocal imaging of the vaginal epithelial microstructure to detect microbicide toxicity.

Authors:  Gracie Vargas; Tuya Shilagard; Rebecca Johnston; Brent Bell; Rachael L Stegall; Kathleen Vincent; Lawrence Stanberry; Massoud Motamedi; Nigel Bourne
Journal:  J Infect Dis       Date:  2009-05-15       Impact factor: 5.226

8.  Low cost, high performance, self-aligning miniature optical systems.

Authors:  Robert T Kester; Todd Christenson; Rebecca Richards Kortum; Tomasz S Tkaczyk
Journal:  Appl Opt       Date:  2009-06-20       Impact factor: 1.980

9.  Handheld tunable focus confocal microscope utilizing a double-clad fiber coupler for in vivo imaging of oral epithelium.

Authors:  Cory Olsovsky; Taylor Hinsdale; Rodrigo Cuenca; Yi-Shing Lisa Cheng; John M Wright; Terry D Rees; Javier A Jo; Kristen C Maitland
Journal:  J Biomed Opt       Date:  2017-05-01       Impact factor: 3.170

10.  Gene transfection efficacy assessment of human cervical cancer cells using dual-mode fluorescence microendoscopy.

Authors:  Jaepyeong Cha; Jing Zhang; Saumya Gurbani; Gyeong Woo Cheon; Min Li; Jin U Kang
Journal:  Biomed Opt Express       Date:  2012-12-18       Impact factor: 3.732
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