| Literature DB >> 12176352 |
Abstract
Phosphorylation of beta-catenin, a central downstream component of the Wnt pathway, by glycogen synthase kinase 3 is essential for its targeted degradation by the proteosome. New studies show that casein kinase 1 primes beta-catenin for subsequent phophorylation by glycogen synthase kinase 3.Entities:
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Year: 2002 PMID: 12176352 DOI: 10.1016/s0960-9822(02)00969-7
Source DB: PubMed Journal: Curr Biol ISSN: 0960-9822 Impact factor: 10.834