Literature DB >> 12170785

5-propynyluracil.diaminopurine: an efficient base-pair for non-enzymatic transcription of DNA.

John C Chaput1, Surajit Sinha, Christopher Switzer.   

Abstract

The Up.D base-pair (5-propynyl uracil.diaminopurine) is found to be more effective at non-enzymatic transcription than the corresponding natural T.A pair; under non-enzymatic reaction conditions where the natural T.A base-pair fails, a DNA template bearing Up efficiently directs the incorporation of D into a product RNA strand.

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Year:  2002        PMID： 12170785     DOI： 10.1039/b204535d

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  8 in total

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2.  Efficient and rapid template-directed nucleic acid copying using 2'-amino-2',3'-dideoxyribonucleoside-5'-phosphorimidazolide monomers.

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3.  A strongly pairing fifth base: oligonucleotides with a C-nucleoside replacing thymidine.

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Journal:  Nucleic Acids Res       Date:  2018-09-19       Impact factor: 16.971

Review 4.  An optimal degree of physical and chemical heterogeneity for the origin of life?

Authors:  Jack W Szostak
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2011-10-27       Impact factor: 6.237

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Authors:  Yevgeny Brudno; David R Liu
Journal:  Chem Biol       Date:  2009-03-27

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Authors:  Jozef Salon; Jiansheng Jiang; Jia Sheng; Oksana O Gerlits; Zhen Huang
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Review 7.  Taming Prebiotic Chemistry: The Role of Heterogeneous and Interfacial Catalysis in the Emergence of a Prebiotic Catalytic/Information Polymer System.

Authors:  Pierre-Alain Monnard
Journal:  Life (Basel)       Date:  2016-11-04

Review 8.  Modified nucleic acids: replication, evolution, and next-generation therapeutics.

Authors:  Karen Duffy; Sebastian Arangundy-Franklin; Philipp Holliger
Journal:  BMC Biol       Date:  2020-09-02       Impact factor: 7.431
  8 in total

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