Literature DB >> 12166853

Generation of anisotropic-smoothness regularization filters for EIT.

Andrea Borsic1, William R B Lionheart, Christopher N McLeod.   

Abstract

In the inverse conductivity problem, as in any ill-posed inverse problem, regularization techniques are necessary in order to stabilize inversion. A common way to implement regularization in electrical impedance tomography is to use Tikhonov regularization. The inverse problem is formulated as a minimization of two terms: the mismatch of the measurements against the model, and the regularization functional. Most commonly, differential operators are used as regularization functionals, leading to smooth solutions. Whenever the imaged region presents discontinuities in the conductivity distribution, such as interorgan boundaries, the smoothness prior is not consistent with the actual situation. In these cases, the reconstruction is enhanced by relaxing the smoothness constraints in the direction normal to the discontinuity. In this paper, we derive a method for generating Gaussian anisotropic regularization filters. The filters are generated on the basis of the prior structural information, allowing a better reconstruction of conductivity profiles matching these priors. When incorporating prior information into a reconstruction algorithm, the risk is of biasing the inverse solutions toward the assumed distributions. Simulations show that, with a careful selection of the regularization parameters, the reconstruction algorithm is still able to detect conductivities patterns that violate the prior information. A generalized singular-value decomposition analysis of the effects of the anisotropic filters on regularization is presented in the last sections of the paper.

Mesh:

Year:  2002        PMID: 12166853     DOI: 10.1109/TMI.2002.800611

Source DB:  PubMed          Journal:  IEEE Trans Med Imaging        ISSN: 0278-0062            Impact factor:   10.048


  8 in total

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Review 3.  Advances in optical spectroscopy and imaging of breast lesions.

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Review 7.  Robust imaging using electrical impedance tomography: review of current tools.

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8.  Structural-functional lung imaging using a combined CT-EIT and a Discrete Cosine Transformation reconstruction method.

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  8 in total

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