| Literature DB >> 12153207 |
You-Chu Wang1, Paris E Georghiou.
Abstract
[structure: see text] The first enantioselective total synthesis of (-)-tejedine (1) is reported. Tejedine is a seco-bisbenzyltetrahydroisoquinoline isolated in 1998 as a minor component from Berberis vulgaris. The synthesis was achieved using a strategy employing four key steps, including a chiral auxiliary-assisted diastereoselective Bischler-Napieralski cyclization.Entities:
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Year: 2002 PMID： 12153207 DOI： 10.1021/ol0261635
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005