Literature DB >> 12150923

Evidence for a mediator of RNA polymerase II transcriptional regulation conserved from yeast to man.

Muriel Boube1, Laurent Joulia, David L Cribbs, Henri-Marc Bourbon.   

Abstract

Mediator complexes (MED) link transcriptional regulators to RNA polymerase II. Here, we summarize the latest advances on the functional organization of yeast Mediator. We argue for the existence of a "universal" Mediator structurally conserved from yeast to man, based on an extensive analysis of sequence databases. Finally, we examine the implications of these observations for the physiological roles of metazoan MED subunits.

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Year:  2002        PMID： 12150923     DOI： 10.1016/s0092-8674(02)00830-9

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  107 in total

Review 1.  Structure and mechanism of the RNA polymerase II transcription machinery.

Authors:  Steven Hahn
Journal:  Nat Struct Mol Biol       Date:  2004-05       Impact factor: 15.369

2.  The activator-recruited cofactor/Mediator coactivator subunit ARC92 is a functionally important target of the VP16 transcriptional activator.

Authors:  Fajun Yang; Rosalie DeBeaumont; Sharleen Zhou; Anders M Näär
Journal:  Proc Natl Acad Sci U S A       Date:  2004-02-24       Impact factor: 11.205

3.  Cyclin-dependent kinase 8 regulates mitotic commitment in fission yeast.

Authors:  Zsolt Szilagyi; Gabor Banyai; Marcela Davila Lopez; Christopher J McInerny; Claes M Gustafsson
Journal:  Mol Cell Biol       Date:  2012-03-26       Impact factor: 4.272

4.  Interaction of Bunyamwera Orthobunyavirus NSs protein with mediator protein MED8: a mechanism for inhibiting the interferon response.

Authors:  Vincent H J Léonard; Alain Kohl; Timothy J Hart; Richard M Elliott
Journal:  J Virol       Date:  2006-10       Impact factor: 5.103

5.  Coactivator cross-talk specifies transcriptional output.

Authors:  Michael T Marr; Yoh Isogai; Kevin J Wright; Robert Tjian
Journal:  Genes Dev       Date:  2006-06-01       Impact factor: 11.361

6.  Structural and functional characterization of PC2 and RNA polymerase II-associated subpopulations of metazoan Mediator.

Authors:  Sohail Malik; Hwa Jin Baek; Weizhen Wu; Robert G Roeder
Journal:  Mol Cell Biol       Date:  2005-03       Impact factor: 4.272

7.  Differential roles of transcriptional mediator complex subunits Crsp34/Med27, Crsp150/Med14 and Trap100/Med24 during zebrafish retinal development.

Authors:  Katrin Dürr; Jochen Holzschuh; Alida Filippi; Anne-Kathrin Ettl; Soojin Ryu; Iain T Shepherd; Wolfgang Driever
Journal:  Genetics       Date:  2006-04-02       Impact factor: 4.562

8.  Host factors that affect Ty3 retrotransposition in Saccharomyces cerevisiae.

Authors:  Michael Aye; Becky Irwin; Nadejda Beliakova-Bethell; Eric Chen; Jennifer Garrus; Suzanne Sandmeyer
Journal:  Genetics       Date:  2004-11       Impact factor: 4.562

9.  Genetic interactions of DST1 in Saccharomyces cerevisiae suggest a role of TFIIS in the initiation-elongation transition.

Authors:  Francisco Malagon; Amy H Tong; Brenda K Shafer; Jeffrey N Strathern
Journal:  Genetics       Date:  2004-03       Impact factor: 4.562

10.  TRAP230/ARC240 and TRAP240/ARC250 Mediator subunits are functionally conserved through evolution.

Authors:  Camilla O Samuelsen; Vera Baraznenok; Olga Khorosjutina; Henrik Spahr; Thomas Kieselbach; Steen Holmberg; Claes M Gustafsson
Journal:  Proc Natl Acad Sci U S A       Date:  2003-05-08       Impact factor: 11.205
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