Literature DB >> 12150816

A mitochondrial Achilles' heel in cancer?

David M Hockenbery1.   

Abstract

Mitochondria are principal actors in apoptosis as central hubs for diverse apoptotic signals. A new paper demonstrates the therapeutic potential of directly engaging these apoptotic pathways by identifying a mitochondrial toxin selective for tumor cells.

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Year:  2002        PMID： 12150816     DOI： 10.1016/s1535-6108(02)00087-9

Source DB:  PubMed          Journal:  Cancer Cell        ISSN： 1535-6108            Impact factor:   31.743


  8 in total

Review 1.  Mitochondrial membrane potential and reactive oxygen species in cancer stem cells.

Authors:  Bei-bei Zhang; Dao-gang Wang; Fen-fen Guo; Chao Xuan
Journal:  Fam Cancer       Date:  2015-03       Impact factor: 2.375

2.  Heterogeneity of mitochondrial membrane potential: a novel tool to isolate and identify cancer stem cells from a tumor mass?

Authors:  Xiao-Qun Ye; Guang-Hui Wang; Gui-Jun Huang; Xiu-Wu Bian; Gui-Sheng Qian; Shi-Cang Yu
Journal:  Stem Cell Rev Rep       Date:  2011-03       Impact factor: 5.739

3.  Rottlerin stimulates apoptosis in pancreatic cancer cells through interactions with proteins of the Bcl-2 family.

Authors:  Izumi Ohno; Guido Eibl; Irina Odinokova; Mouad Edderkaoui; Robert D Damoiseaux; Moussa Yazbec; Ravinder Abrol; William A Goddard; Osamu Yokosuka; Stephen J Pandol; Anna S Gukovskaya
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2009-09-17       Impact factor: 4.052

4.  Chronic CSE treatment induces the growth of normal oral keratinocytes via PDK2 upregulation, increased glycolysis and HIF1α stabilization.

Authors:  Wenyue Sun; Steven S Chang; Yumei Fu; Yan Liu; Joseph A Califano
Journal:  PLoS One       Date:  2011-01-19       Impact factor: 3.240

5.  The energy blocker inside the power house: Mitochondria targeted delivery of 3-bromopyruvate.

Authors:  Sean Marrache; Shanta Dhar
Journal:  Chem Sci       Date:  2015-03       Impact factor: 9.825

Review 6.  Mitoepigenetics and Its Emerging Roles in Cancer.

Authors:  Zhen Dong; Longjun Pu; Hongjuan Cui
Journal:  Front Cell Dev Biol       Date:  2020-01-23

Review 7.  Mitochondrial defects in cancer.

Authors:  Jennifer S Carew; Peng Huang
Journal:  Mol Cancer       Date:  2002-12-09       Impact factor: 27.401

8.  99mTc-MIBI uptake as a marker of mitochondrial membrane potential in cancer cells and effects of MDR1 and verapamil.

Authors:  Jin Won Park; Sun-Pyo Hong; Jin Hee Lee; Seung Hwan Moon; Young Seok Cho; Kyung-Ho Jung; Jeeyun Lee; Kyung-Han Lee
Journal:  PLoS One       Date:  2020-02-12       Impact factor: 3.240
  8 in total

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