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Literature DB >> 20306158

Heterogeneity of mitochondrial membrane potential: a novel tool to isolate and identify cancer stem cells from a tumor mass?

Xiao-Qun Ye¹, Guang-Hui Wang, Gui-Jun Huang, Xiu-Wu Bian, Gui-Sheng Qian, Shi-Cang Yu.

Abstract

It is believed that cancer stem cells (CSCs) are precursors for the formation, development, and recurrence of malignant tumors. However, it has proven difficult to isolate and enrich these rare, undifferentiated cells from heterogeneous tumor masses. With some existing reports and preliminary results in mind, we hypothesized that the mitochondrial membrane potential within a tumor mass was heterogeneous and could be used as a tool to isolate and enrich CSCs.

Entities: Disease

Mesh：

Substances：

Year: 2011 PMID： 20306158 DOI： 10.1007/s12015-010-9122-9

Source DB: PubMed Journal: Stem Cell Rev Rep ISSN： 2629-3277 Impact factor: 5.739

61 in total

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Journal: Stem Cell Rev Rep Date: 2009-04-03 Impact factor: 5.739

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Journal: J Cell Biochem Date: 1993-11 Impact factor: 4.429

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8. Resistance to cytotoxic chemotherapy-induced apoptosis in side population cells of human oral squamous cell carcinoma cell line Ho-1-N-1.

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Journal: Int J Oncol Date: 2009-08 Impact factor: 5.650

9. Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells.

Authors: Zhizhong Li; Shideng Bao; Qiulian Wu; Hui Wang; Christine Eyler; Sith Sathornsumetee; Qing Shi; Yiting Cao; Justin Lathia; Roger E McLendon; Anita B Hjelmeland; Jeremy N Rich
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Journal: Cancer Res Date: 2007-05-15 Impact factor: 12.701

19 in total

1. Mitaplatin increases sensitivity of tumor cells to cisplatin by inducing mitochondrial dysfunction.

Authors: Xue Xue; Song You; Qiang Zhang; Yan Wu; Guo-Zhang Zou; Paul C Wang; Yu-Liang Zhao; Yan Xu; Lee Jia; Xiaoning Zhang; Xing-Jie Liang
Journal: Mol Pharm Date: 2012-02-13 Impact factor: 4.939

2. Quantitative Imaging of Morphometric and Metabolic Signatures Reveals Heterogeneity in Drug Response of Three-Dimensional Mammary Tumor Spheroids.

Authors: V Krishnan Ramanujan
Journal: Mol Imaging Biol Date: 2019-06 Impact factor: 3.488

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Authors: Yao-An Shen; Wai-Hou Li; Po-Hung Chen; Chun-Lin He; Yen-Hou Chang; Chi-Mu Chuang
Journal: Am J Transl Res Date: 2015-05-15 Impact factor: 4.060

Review 4. Can nanomedicines kill cancer stem cells?

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Journal: Adv Drug Deliv Rev Date: 2013-10-10 Impact factor: 15.470

5. Mitochondrial metabolism directs stemness and differentiation in P19 embryonal carcinoma stem cells.

Authors: I Vega-Naredo; R Loureiro; K A Mesquita; I A Barbosa; L C Tavares; A F Branco; J R Erickson; J Holy; E L Perkins; R A Carvalho; P J Oliveira
Journal: Cell Death Differ Date: 2014-05-16 Impact factor: 15.828

Review 6. Targeting cancer stem cells from a metabolic perspective.

Authors: Yao-An Shen; Siao-Cian Pan; I Chu; Ruo-Yun Lai; Yau-Huei Wei
Journal: Exp Biol Med (Maywood) Date: 2020-02-26

Review 7. Strategies for isolating and enriching cancer stem cells: well begun is half done.

Authors: Jiang-Jie Duan; Wen Qiu; Sen-Lin Xu; Bin Wang; Xian-Zong Ye; Yi-Fang Ping; Xia Zhang; Xiu-Wu Bian; Shi-Cang Yu
Journal: Stem Cells Dev Date: 2013-05-09 Impact factor: 3.272

8. Peptide nucleic acids targeting mitochondria enhances sensitivity of lung cancer cells to chemotherapy.

Authors: Sheng-Song Chen; Xiao-Yun Tu; Li-Xia Xie; Lv-Ping Xiong; Juan Song; Xiao-Qun Ye
Journal: Am J Transl Res Date: 2018-09-15 Impact factor: 4.060

9. Metabolic reprogramming orchestrates cancer stem cell properties in nasopharyngeal carcinoma.

Authors: Yao-An Shen; Chia-Yu Wang; Yi-Tao Hsieh; Yann-Jang Chen; Yau-Huei Wei
Journal: Cell Cycle Date: 2015 Impact factor: 4.534

10. Hypoxic and Reoxygenated Microenvironment: Stemness and Differentiation State in Glioblastoma.

Authors: Mariana Maier Gaelzer; Mariana Silva Dos Santos; Bárbara Paranhos Coelho; Alice Hoffman de Quadros; Fabrício Simão; Vanina Usach; Fátima Costa Rodrigues Guma; Patrícia Setton-Avruj; Guido Lenz; Christianne G Salbego
Journal: Mol Neurobiol Date: 2016-10-06 Impact factor: 5.590