Literature DB >> 12147514

Accumulation of inorganic polyphosphate in phoU mutants of Escherichia coli and Synechocystis sp. strain PCC6803.

Tomohiro Morohoshi1, Tatsuya Maruo, Yoko Shirai, Junichi Kato, Tsukasa Ikeda, Noboru Takiguchi, Hisao Ohtake, Akio Kuroda.   

Abstract

The biological process for phosphate (P(i)) removal is based on the use of bacteria capable of accumulating inorganic polyphosphate (polyP). We obtained Escherichia coli mutants which accumulate a large amount of polyP. The polyP accumulation in these mutants was ascribed to a mutation of the phoU gene that encodes a negative regulator of the P(i) regulon. Insertional inactivation of the phoU gene also elevated the intracellular level of polyP in Synechocystis sp. strain PCC6803. The mutant could remove fourfold more P(i) from the medium than the wild-type strain removed.

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Year:  2002        PMID: 12147514      PMCID: PMC124021          DOI: 10.1128/AEM.68.8.4107-4110.2002

Source DB:  PubMed          Journal:  Appl Environ Microbiol        ISSN: 0099-2240            Impact factor:   4.792


  18 in total

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Journal:  J Biol Chem       Date:  1992-11-05       Impact factor: 5.157

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Review 3.  Inorganic polyphosphates in biology: structure, metabolism, and function.

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Journal:  J Bacteriol       Date:  1999-05       Impact factor: 3.490

5.  Use of the rep technique for allele replacement to construct mutants with deletions of the pstSCAB-phoU operon: evidence of a new role for the PhoU protein in the phosphate regulon.

Authors:  P M Steed; B L Wanner
Journal:  J Bacteriol       Date:  1993-11       Impact factor: 3.490

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Authors:  B L Wanner
Journal:  J Cell Biochem       Date:  1993-01       Impact factor: 4.429

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Authors:  K Poole; R E Hancock
Journal:  Eur J Biochem       Date:  1984-11-02

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Authors:  R A Allan; J J Miller
Journal:  Can J Microbiol       Date:  1980-08       Impact factor: 2.419

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Journal:  J Mol Biol       Date:  1985-07-20       Impact factor: 5.469

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  36 in total

1.  A novel mechanism of osmosensing, a salt-dependent protein-nucleic acid interaction in the cyanobacterium Synechocystis Species PCC 6803.

Authors:  Jens F Novak; Marit Stirnberg; Benjamin Roenneke; Kay Marin
Journal:  J Biol Chem       Date:  2010-12-01       Impact factor: 5.157

2.  Concerted changes in gene expression and cell physiology of the cyanobacterium Synechocystis sp. strain PCC 6803 during transitions between nitrogen and light-limited growth.

Authors:  Eneas Aguirre von Wobeser; Bas W Ibelings; Jasper Bok; Vladimir Krasikov; Jef Huisman; Hans C P Matthijs
Journal:  Plant Physiol       Date:  2011-01-04       Impact factor: 8.340

3.  Mutations in Escherichia coli Polyphosphate Kinase That Lead to Dramatically Increased In Vivo Polyphosphate Levels.

Authors:  Amanda K Rudat; Arya Pokhrel; Todd J Green; Michael J Gray
Journal:  J Bacteriol       Date:  2018-02-23       Impact factor: 3.490

4.  Acquisition of the Phosphate Transporter NptA Enhances Staphylococcus aureus Pathogenesis by Improving Phosphate Uptake in Divergent Environments.

Authors:  Jessica L Kelliher; Jana N Radin; Kyle P Grim; Paola K Párraga Solórzano; Patrick H Degnan; Thomas E Kehl-Fie
Journal:  Infect Immun       Date:  2017-12-19       Impact factor: 3.441

5.  Synthetic lethality with the dut defect in Escherichia coli reveals layers of DNA damage of increasing complexity due to uracil incorporation.

Authors:  Helen Ting; Elena A Kouzminova; Andrei Kuzminov
Journal:  J Bacteriol       Date:  2008-06-27       Impact factor: 3.490

6.  Essential Genes Predicted in the Genome of Rubrivivax gelatinosus.

Authors:  Patrick D Curtis
Journal:  J Bacteriol       Date:  2016-07-28       Impact factor: 3.490

7.  Identification of the PhoB Regulon and Role of PhoU in the Phosphate Starvation Response of Caulobacter crescentus.

Authors:  Emma A Lubin; Jonathan T Henry; Aretha Fiebig; Sean Crosson; Michael T Laub
Journal:  J Bacteriol       Date:  2015-10-19       Impact factor: 3.490

8.  Differential regulation of polyphosphate genes in Pseudomonas aeruginosa.

Authors:  Nicolás Federico Villamil Munévar; Luiz Gustavo de Almeida; Beny Spira
Journal:  Mol Genet Genomics       Date:  2016-10-15       Impact factor: 3.291

9.  Depletion of the FtsH1/3 Proteolytic Complex Suppresses the Nutrient Stress Response in the Cyanobacterium Synechocystis sp strain PCC 6803.

Authors:  Vendula Krynická; Jens Georg; Philip J Jackson; Mark J Dickman; C Neil Hunter; Matthias E Futschik; Wolfgang R Hess; Josef Komenda
Journal:  Plant Cell       Date:  2019-10-15       Impact factor: 11.277

10.  Polyphosphate accumulation in Escherichia coli in response to defects in DNA metabolism.

Authors:  Luciana Amado; Andrei Kuzminov
Journal:  J Bacteriol       Date:  2009-10-16       Impact factor: 3.490

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