| Literature DB >> 12143001 |
George Duker-Eshun, Jerzy W Jaroszewski, William A Asomaning, Francis Oppong-Boachie, Carl Erik Olsen, S Brøgger Christensen.
Abstract
Bioguided fractionation of extracts of Aframomum latifolium and A. sceptrum (Zingiberaceae) resulted in isolation of (+)-( S)-nerolidol and seven labdanes, coronarin B, galanal A and B, galanolactone, ( E)-8beta,17-epoxylabd-12-ene-15,16-dial, (+)-( E)-labda-8(17), 12-diene-15,16-dial and its diethyl acetal, the latter being presumably an isolation artefact. The labdanes show a modest in vitro activity against a chloroquine-sensitive Plasmodium falciparum strain.Entities:
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Year: 2002 PMID： 12143001 DOI： 10.1055/s-2002-32888
Source DB: PubMed Journal: Planta Med ISSN： 0032-0943 Impact factor: 3.352