Bruce M Buerk1, Elmer Tu. 1. Department of Ophthalmology and Visual Sciences, UIC Eye Center, University of Illinois at Chicago, 1855 W. Taylor, Chicago, IL 60612, U.S.A.
Abstract
PURPOSE: To report confocal microscopy findings of a patient with multiple myeloma crystalline keratopathy and the response to treatment. METHODS: Confocal microscopy images of the cornea were taken OU and the corneal crystals analyzed using the Cell Counter software. RESULTS: Numerous hyperreflective globules 6-11 nm in size were located within the corneal epithelium and anterior stroma. These crystals obscured normal architectural detail of the cornea. After 6 months of chemotherapy, confocal microscopy was repeated and demonstrated decrease in the size and number of hyperreflective globules. CONCLUSION: Confocal microscopy can enable the clinician to monitor the clinical response of multiple myeloma crystalline keratopathy to chemotherapeutic agents.
PURPOSE: To report confocal microscopy findings of a patient with multiple myeloma crystalline keratopathy and the response to treatment. METHODS: Confocal microscopy images of the cornea were taken OU and the corneal crystals analyzed using the Cell Counter software. RESULTS: Numerous hyperreflective globules 6-11 nm in size were located within the corneal epithelium and anterior stroma. These crystals obscured normal architectural detail of the cornea. After 6 months of chemotherapy, confocal microscopy was repeated and demonstrated decrease in the size and number of hyperreflective globules. CONCLUSION: Confocal microscopy can enable the clinician to monitor the clinical response of multiple myeloma crystalline keratopathy to chemotherapeutic agents.
Authors: Sibel Kocabeyoglu; Mehmet C Mocan; Ibrahim C Haznedaroglu; Aysegul Uner; Enes Uzunosmanoglu; Murat Irkec Journal: Indian J Ophthalmol Date: 2014-09 Impact factor: 1.848
Authors: Kitti Kormányos; Klaudia Kovács; Orsolya Németh; Gábor Tóth; Gábor László Sándor; Anita Csorba; Cecília Nóra Czakó; László Módis; Achim Langenbucher; Zoltán Zsolt Nagy; Gergely Varga; László Gopcsa; Gábor Mikala; Nóra Szentmáry Journal: J Clin Med Date: 2022-03-26 Impact factor: 4.241