| Literature DB >> 12127531 |
Wenqian Yang1, Shouhai Gao, Xingming Gao, Vishnu Vardhan Reddy Karnati, Weijuan Ni, Binghe Wang, W Borden Hooks, John Carson, Brent Weston.
Abstract
A series of fluorescent diboronic acids was synthesized in nine steps as potential sensors for sialyl Lewis X (sLex). The fluorescent binding studies of these sensors with sLex were carried out in a mixed aqueous solution. Compound 7e was found to show the strongest fluorescence enhancement upon binding with sLex. Using cell cultures, 7e was shown to label sLex-expressing HEPG2 cells at 1 microM, while non-sLex-expressing cells were not labeled.Entities:
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Year: 2002 PMID： 12127531 DOI： 10.1016/s0960-894x(02)00339-6
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823